Published in Medical Letter on the CDC and FDA, March 30th, 2003
According to a study from the United States, "This paper describes a new statistical test of non-inferiority in clinical trials of anti-infective medications. The test allows the inferiority limit, delta, to vary with the underlying success rates."
"The test is a simple modification of the standard fixed-delta test, and its parameters can be adjusted to yield the fixed-delta test, a test similar to the FDA's Points-to-Consider procedure, or a test with nearly constant power values over a range of success rates," said Kem F. Phillips at Advanced Biologics LLC in Lambertville,...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Medical Letter on the CDC and FDA
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.