Neisseria Gonorrhoeae
Porin variation small among clinical isolates of Neisseria gonorrhoeae
Published in Medical Letter on the CDC and FDA, June 1st, 2003
According to recent research from the United States, "The Neisseria gonorrhoeae porin protein (Por) is a potential vaccine target and is the antigenic determinant for serovar typing. Two classes of Por, PIA and PIB, and antigenically distinct variants within each class result from sequence variations in the por gene variable regions (VRs) encoding surface-exposed loops. Oligonucleotide probes to five VRs of each class were used in checkerboard hybridizations to type 282 clinical gonococcal isolates selected from strains collected over the...
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