Endocrinology
GLP-1 receptor agonists are growth factors for pancreatic islet beta cells
Published in Medical Letter on the CDC and FDA, June 8th, 2003
"Glucagon-like peptide-1 (GLP-1) is an incretin hormone that, when given exogenously, is capable of normalizing blood glucose in individuals with type 2 diabetes. Until recently most of the research on this compound had been related to its insulinotropic properties. However, GLP-1 also regulates insulin synthesis and proinsulin gene expression, as well as the components of the glucose-sensing machinery," scientists in the United States report.
"In addition to regulating insulin release, it is involved in regulating the secretion of at least two other islet...
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