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Stem Cell Research

Novel neural cell model enables study of JC virus susceptibility

Published in Medical Letter on the CDC and FDA, June 29th, 2003

A novel stem cell model allows scientists to examine the JC virus susceptibility of neural cells.

In a study from the United States, "multipotential human central nervous system progenitor cells, isolated from human fetal brain tissue by selective growth conditions, were cultured as undifferentiated, attached cell layers."

"Selective differentiation yielded highly purified populations of neurons or astrocytes," according to C.A. Messam and coauthors at the National Institute of Neurological Disorders and Stroke, who described "the novel use of this cell culture model to study cell type-specific recognition of a human neurotropic virus, JC virus," in...

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