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Medical Letter on the CDC and FDA

Susan Hasty, Publisher

Table of Contents . . . July 6th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications

Monkeypox - Smallpox vaccination recommended for those exposed to virus

Vaccine Development - Human vaccine strain of lamb rotavirus (Chinese) NSP4 gene sequenced

African Trypanosomiasis - WHO criteria for trypanosomiasis can be improved by measuring IgM in the CSF

Epilepsy Therapy - Pharmacology of topiramate and lamotrigine compared with phenobarbital

Measles Vaccine - Measles antibodies interfere with immune response in revaccinated adults

SARS - Death rate lower in countries responding aggressively to initial outbreak

Adverse Drug Effects - Age-related differences found in the side effect profile of citalopram

Amebic Dysentery - An amebic thiol-specific antioxidant prevents killing by host mononuclear ROS

Anthrax - FDA clears IND for anthrax vaccine candidate

Asthma - Asthma in high percentage of North Carolina children undiagnosed, study shows

Breast Cancer - Antitumor activity reported for ABI-007 in patients resistant to taxane

Chagas Disease - Chronically infected individuals have an imbalance of cytokines to antioxidants

Counterfeit Drugs - U.S. Food and Drug Administration says problem is growing

DNA Damage - Exposure to one, minimal erythema dose of UV damaged skin DNA of all subjects

Diabetes Genomics and Genetics - Interleukin-6 promoter polymorphism associated with type 2 diabetes

Diet and Nutrition - Efforts underway to increase whole-grain consumption in the United States

Disease Transmission - WHO underestimates HIV exposure from dirty needles, researcher says

Epidemiology - Japanese kids gaining body fat, heart risks like Western counterparts

Epidemiology - Race, ethnicity increase risk for STDs in those otherwise at lowest risk

Epidemiology - WHO: Concerted global action is the only answer to rising cancer deaths

Familial Cancer - Ratio of reported-to-expected cancer rates in family members approximately 0.7

HIV/AIDS Education - Community HealthCorps members assist in youth HIV/AIDS prevention education

HIV/AIDS Therapy - Enfuvirtide is first fusion inhibitor for treating patients with HIV

Influenza - Epidemiologic data for 2002-03 flu season reported

Influenza Vaccine - Influenza surveillance in Europe and its future reviewed

Malaria - Bed nets dramatically reduce malaria exposure in Kenyan infants

Malaria - Malaria reduced in pregnant women by permethrin-treated bed nets in Kenya

Malaria - Permethrin-treated bed nets reduce local population of malaria vectors

Malaria - Permethrin-treated bed nets reduce mortality in young children in Kenya

Malaria Therapy - Home care feasible in Guinea Bissau

Mania - Criteria defining antimanic drugs discussed

Measles Vaccine - Eradication of measles in the Western Pacific Region close to reality

Measles Vaccine - Measles eradicated in Haiti after outbreak in 2000

Monkeypox - Case of possible human-to-human transmission under investigation

Monkeypox - First outbreak of human infection in Western Hemisphere reported

Occupational Health Hazards - Respiratory tuberculosis mortality risk evaluated by job type

Organ Transplantation - Immune cell testing used as adjunct to drug monitoring in transplantation patients

Pediatrics - Government statistics underestimate neonatal mortality in rural western Kenya

Pediatrics - Permethrin-treated bed nets reduce morbidity in young children in Kenya

Pediatrics - Permethrin-treated bed nets reduce sick child visits for malaria

Polio - Eradication efforts should continue in southern Africa, report says

Polychlorinated Biphenyl Toxicity - Exposure to PCB may alter brain chemicals such as protein kinases

Public Health - GSK, ABC Radio, and DHHS to improve health among communities of color

Public Health - Impact of violence and prevention strategies discussed at symposium

Public Health - Pool inspection data could be used more effectively

Regulatory Issues - New rules speed generic drugs to market in U.S.

SARS - CDC confirms Singapore is in the clear

SARS - Low-dose interferon alpha lozenges to be used against SARS

SARS - WHO says SARS outbreak could be coming to an end

Safety Equipment - Agencies team up to ensure safety of first responder gas masks

Trypanosoma Cruzi - Of many Trypanosoma found, several appear to be product of recombination

Tuberculosis - Eli Lilly and Co. unveils global partnership to battle MDR-TB

Tumoral Calcinosis - Angiography shows margins, which influences management and surgical approach

Virology - Topology of epitope-tagged F13L protein elucidated

West Nile Virus - Food and Drug Administration says screening tests will be ready to protect blood supply

Zoonoses - Exotic diseases transmitted from animals to humans are public health threat

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