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Trypanosoma Cruzi

Of many Trypanosoma found, several appear to be product of recombination

Published in Medical Letter on the CDC and FDA, July 6th, 2003

There are many Trypanosoma cruzi subgroups, but some appear to be product of genetic recombination events.

"A role for parasite genetic variability in the spectrum of Chagas disease is emerging but not yet evident, in part due to an incomplete understanding of the population structure of Trypanosoma cruzi. To investigate further the observed genotypic variation at the sequence and chromosomal levels in strains of standard and field-isolated T. cruzi, we have undertaken a comparative analysis of 10 regions of the genome from 2 isolates representing T. cruzi I (Dm28c and Silvio X10) and 2 isolates from T. cruzi 11 (CL Brener and...

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