Chronic Granulomatous Disease
Catalase negative Haemophilus species can be virulent
Published in Medical Letter on the CDC and FDA, July 13th, 2003
"Chronic granulomatous disease (CGD) is a rare inherited disorder in which phagocytes are incapable of generating bactericidal-reactive oxygen derivatives. Typically, these patients are susceptible to life threatening infections of catalase-producing organisms," scientists in the United States report.
"Haemophilus species, particularly H. paraphrophilus, are not associated with CGD infections, because these organisms rarely if ever produce catalase. Haemophilus species are part of the indigenous oral microbial flora and,...
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