Transplantation

Mechanism of xenotransplantation rejection investigated

Published in Medical Letter on the CDC and FDA, August 24th, 2003

The mechanism of xenotransplantation rejection was investigated by scientists at the U.S. Food and Drug Administration.

"Xenotransplantation, especially using porcine sources, has been proposed as a means to alleviate the shortage of human organs for transplantation. NK cells appear to be important mediators of the xenogeneic immune responses, including the human anti-pig response. Having previously established the redox regulation of NK cell activity against tumor target cells, we now report that the interaction of human NK cells with porcine target cells is also regulated by redox," scientists in the United States report.

"Thiol-deprivation...

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Source: Medical Letter on the CDC and FDA (2003-08-24)

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