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Medical Letter on the CDC and FDA

Susan Hasty, Publisher

Table of Contents . . . September 7th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications

HIV/AIDS Epidemiology - Prevalence of HIV infection increasing in older Americans

Malaria - Exoerythrocytic stages of Plasmodium inui shortti shown in new world monkeys

HIV/AIDS Diagnosis - Finger-stick HIV test is accurate and acceptable to women in Thailand

Herpesvirus - Herpesvirus 8 infection linked to hepatitis B and HIV infections in Ugandans

Pharmacokinetics - FDA incentive program improves study of medications for children

Pneumococcal Vaccine - 23-Valent polysaccharide pneumococcal vaccine not effective in Navajo adults

Allergy Medicine - Protein digestibility related to allergenicity

Antibiotic Resistance - World Health Organization: Farmers should cut antibiotic use

Asthma - Labeling changes required for drug products that contain salmeterol

Blood Safety - All donations now screened for West Nile in U.S.

Cancer Therapy - ImClone, Bristol-Myers file application to approve Erbitux

Complementary and Alternative Medicine - Study calls for major reforms in marketing of ephedra

Diabetic Nephropathy - Prevention of the development and progression of renal disease reviewed

Diagnostics - Effect of trabecular material on backscatter from cancellous bone reported

Drug Importation - Montana moves to halt Canada drugs by mail

Drug Resistance - Epidemiology of sporadic bloody diarrhea in rural Western Kenya reported

Environmental Health - Aerosolized mycobacteria may underlie respiratory disease outbreaks

Epidemiology - Work done by Emerging Infections Programs outlined

Fitness - Physical activity definitions broadened to include daily activities

Food-borne Disease - All Vibrio vulnificus isolates from market oysters are virulent

Food-borne Disease - Handlers of E. coli-infected ground beef can contaminate lettuce

Fungal Therapy - Caspofungin is first approved agent in new class of antifungals

Guillain Barre Syndrome - Acute flaccid paralysis may be caused by West Nile virus infection

HIV/AIDS Risk Factor - Sexual behavior labels usefulness limited in sexually active gay men

HIV/AIDS Risk Factor - TNF-alpha-inducible mutation in interferon gamma gene linked to rapid HIV progression

HIV/AIDS Therapy - Novel stavudine derivatives synthesized

Infectious Disease -  Clostridium species not significant cause of pediatric diarrhea in Brazil

Infectious Disease - Dengue virus serotype 3 viral evolution elucidated

Medical Equipment - FDA approves stair-climbing wheelchair

Medicare - CMS proposes new rules to pay appropriately for covered drugs

Meningitis - West Nile possible, but not probable, cause of aseptic meningitis

Microfluidic Device - Microfluidic device can be programmed for adsorption and release of proteins

Monkeypox - Researchers to take blood samples from victims for study

Parasitic Disease - Schistosomiasis symptoms in Nigeria include gynecological manifestations

Prostate Cancer - Beta-catenin induces hyperplasias and squamous transdifferentiation

Public Health - Illiterate and poor in Brazil have lower life expectancy

Rabies - Rabies reported among infrequently affected mammalian carnivores in U.S.

Regulatory Issues - FDA pledging get-tough stance with drug over-promotion

Schizophrenia - Illness could cause patients to forget their medication

Sexually Transmitted Diseases - Report finds low condom use, HIV testing in NYC

Smallpox - Vaccine provides lifelong immunity

Smallpox - Voluntary shots may not protect

Smallpox Vaccine - Encephalitis is complication of smallpox vaccination

Smallpox Vaccine - Many aspects of smallpox vaccination reviewed

Toxin Screen - A fluorescent immunoassay can detect enterotoxin B better than ELISA

Tuberculosis Genomics and Genetics - DNA repair gene mutations may improve mycobacterial adaption

Utilization - Aging boomers drive up doctor visits

Vaccine Adjuvant - Mixture of CpG oligodeoxynucleotides may be needed for effective vaccine

West Nile Virus - Clinical trial cleared for NeuGene against virus; financial results reported

West Nile Virus - Vaccine said to be effective in mice

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