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HIV/AIDS Diagnosis

Field evaluation of mobility assay for subtyping of HIV-1 described

Published in Medical Letter on the CDC and FDA, September 14th, 2003

Field evaluation of the gag-based heteroduplex mobility assay for genetic subtyping of circulating recombinant forms of human immunodeficiency virus type 1 described in the Ivory Coast.

According to recent research published in the Journal of Clinical Microbiology, "The gag-based heteroduplex mobility assay (gag-HMA) was evaluated for its ease and reliability in subtyping circulating recombinant forms (CRFs) of human immunodeficiency virus type 1 (HIV-1) in Cote d'Ivoire. One hundred thirty-two plasma samples were analyzed blindly for HIV-1 subtypes by sequencing the pol gene and by gag-HMA. DNA sequencing was used as the 'gold standard.'"

"Of...

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