Adverse Drug Reactions
Capecitabine induces pancreatitis in breast cancer patient
Published in Medical Letter on the CDC and FDA, September 21st, 2003
According to recent research published in the journal Pharmacotherapy, "A 47-year-old woman with metastatic breast cancer developed acute pancreatitis while receiving capecitabine. She had been receiving capecitabine 2,000 mg/m2/day; however, when the dosage was increased to 2,500 mg/m2/day (the maximum dosage approved by the Food and Drug Administration) she experienced abdominal pain and cramping. These symptoms were followed by nausea and vomiting, palmar-plantar erythrodysesthesia (hand-foot syndrome), and mucositis, resulting in admission to the hospital."
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