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Alzheimer Disease

T-cell reactivity to amyloid beta increases with age

Published in Medical Letter on the CDC and FDA, October 5th, 2003

T-cell reactivity to amyloid beta increases with age in many people and may open avenues of therapeutic and preventive treatments for Alzheimer disease.

According to published research from the United States, "Alzheimer disease (AD) is characterized by the progressive accumulation of amyloid beta protein (A-beta) in areas of the brain serving cognitive functions such as memory and language. The first of two separate reports reveals that intrinsic T-cell reactivity to the self-antigen A-beta exists in many humans and increases with age. This finding has implications for the design of A-beta vaccines."

"The second report demonstrates that a number of...

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