Human Immunodeficiency Virus
Virus entry is potential target for anti-HIV intervention
Published in Medical Letter on the CDC and FDA, October 26th, 2003
"The replicative cycle of the human immunodeficiency virus (HIV) can be interrupted at several stages. Until recently only the viral reverse transcriptase and protease were the only enzymes targeted by antiretroviral agents. However, the first HIV entry inhibitor (T-20, Enfuvirtide, Fuseon) to be used in humans has been approved by the Food and Drug Administration (FDA)," a scientist writing in the journal Current Medicinal Chemistry reports.
"The HIV entry process is considered as an attractive target for chemotherapeutic intervention, as blocking HIV entry into its target cell...
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