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Medical Letter on the CDC and FDA

Susan Hasty, Publisher

Table of Contents . . . November 16th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications

Smallpox - Orthopoxviruses detected using microarrays of immobilized oligonucleotides

Vaccine Development - Simultaneous measurement of pneumococcal polysaccharide antibodies reported

Antimicrobials - Antibiotic management program causes pseudo-outbreak of nosocomial infections

Drug Resistance - Multidrug-resistant Neisseria gonorrhoeae reported in Hawaii

Tobacco Use - Five tobacco-specific nitrosamines in cigarette smoke quantified

Addiction Medicine - Cost and noncompliance contribute to U.S. physicians' low use of naltrexone

Air Filtration - Hong Kong hospitals get new tool for the fight against SARS

Alzheimer Disease - FDA approves memantine (Namenda)

Anthrax - Postal workers sue Bayer, hospitals over antibiotic

Anthrax - SBIR grant from NIAID awarded to expand development of antibodies

Attention Deficit Hyperactivity Disorder - Patent issued for treatment of attention-deficit disorder and autism

Bacteriology - High rate of surgical-site infections found at Tanzanian medical center

Biotechnology - Impact of biotechnology on future of regulatory toxicology reported

Breast Cancer - SenoScan TrueView system approved for screening with CADx Systems

Breast Cancer - Surgical biopsies in U.S. double that of Britain - for same detection rate

Breast Implant - FDA panel recommends approval of gel-filled breast implants

Campylobacter - Thermophilic Campylobacter species identified by microarray technique

Cancer Therapy - Granisetron reduces chemotherapy-induced nausea and vomiting

Candidiasis - Assay for diagnosis of disseminated candidiasis developed

Cervical Cancer - Study suggests many women can safely extend screening interval to 3 years

Colorectal Cancer - FDA to review BLA for Erbitux

Counterfeit Pharmaceuticals - Technology can authenticate drug pedigree

Cytokines - Immunoassay for multiple cytokines is quick and accurate

Dermatology - Dermatological aspects of successful hand disinfection program described

Diagnostics - Bioequivalence of Salurin similar to Lasix

Diet and Nutrition - Diet of U.S. adults lacking in magnesium

Electrocardiograms - Resting electrocardiogram approved for sale in the U.S.

Exercise - Mix of factors related to physical activity among minority women

Fertility - Survey: Americans in favor of embryo donation, but education needed

Finance - Autoimmune disease drug maker secures $10.6M in private placement

Finance - Company reports increased third quarter revenue; Aloxi commercial launch underway

Flu Shots - Company donates influenza vaccine to support CDC campaigns

Food-borne Disease - Semiquantitative PCR enables estimation of shellfish NLV contamination

Food-borne Illness - Keeping ready-to-eat foods cold may be the key to reducing listeriosis

Food-borne Illness - Outbreak of botulism traced from food sold at Texas salvage store

Food-borne Illness - Putrescine is effective chemical indicator of decomposition in Penaeid shrimp

HIV Prevention - U.S. agency opens Beijing office to help fight AIDS amid new candor by China

HIV/AIDS - No World Vision purchase from Calypte Biomedical

Hantavirus - Experimental vaccine elicits strong antibody response in primates

Hepatitis C Virus - Pre-filled interferon pen for hepatitis C receives FDA marketing approval

Infectious Disease - U.N. fund commits US$623 million to fight AIDS, TB, malaria

Influenza - Phase III data for influenza vaccine presented at conference

Influenza Vaccine - Health Canada gives approval to begin field trial of FluINsure

Injury Prevention - $3.6 million awarded to UNC injury center to establish violence training program

Insulin - Rho subfamily of G proteins regulates insulin secretion from beta cells

Insulin Sensitizer - Update given on Sucanon regulatory approval, production in Mexico

Listeria -  Listeria monocytogenes strains from three genotypic lineages studied

Macular Degeneration - FDA clears 810 Nanometer Infrared Diode Photocoagulator

Measles - Global leaders intensify commitment to prevent leading childhood killer

Medical Staffing - MSSI-TeleScience wins Pentagon contract to provide medical personnel

Multiple Myeloma - Orphan drug designation granted for Saha, phase I trial initiated

Nicotine Addiction - Novelty-seeking teens more receptive to tobacco advertising

Nosocomial Infection -  A. baumannii antibiotic resistance does not extend to disinfectants

Nosocomial Infection - Air-handling system blamed for invasive Aspergillus outbreak in operating theater

Nosocomial Infection - Pennsylvania state agency not disclosing hospital infections

Nutrition - Coral-calcium supplier asks FDA to allow more extensive claims for calcium

Obesity - FDA, restaurants discuss nutrition info

Occupational Health Risks - Growing evidence for increased risk of breast, skin cancers among cabin crew

Oncology - Genes and new therapies can be studied in models of von Hippel-Lindau disease

Oral Warts - IND application filed to test oral interferon alpha

Osteoporosis - Estrogen patch for osteoporosis prevention currently under FDA review

Parkinson Disease - Parkinson disease mutant degraded through ubiquitin-proteasome system

Pediatric Screening - Increased testing helps uncover hearing problems in infants

Personnel - Microbiological test company names Sarath Krishnaswamy VP, development

Prescription Drug Importation - FDA questions Vermont city's buying low-cost Canadian drugs

Prostate Cancer - Altered cytochrome c oxidase subunit levels found in prostate cancer

Proteomics - Proteins associated with inactive X chromosome reported

Proteomics - SIN3 deacetylase complex represses mitochondrial protein genes

Regulatory Issues - FDA proposes steps to assure the safety, efficacy of some unapproved medicines

Rotavirus - Study examines prevalence in Asian children

SARS - Alliance targets development of hyperimmune specific for SARS

SARS - CDC releases draft version of new SARS plan

SARS - Chinese survivors report bone damage

SARS - WHO: No evidence virus is airborne

Salmonella - Hand stirring during homogenization improves detection of Salmonella

Salmonella - Preenrichment more sensitive than agar plating for Salmonella detection

Scabies - Ivermectin effective for scabies treatment

Silicone Breast Implants - FDA panel votes to add conditions to sale of silicone implants

Skin Cancer - Independent task forces release recommendations for prevention efforts

Smoking Cessation - Switch to low-tar cigarettes doesn't help smokers quit

Social Anxiety Disorder - FDA approves Paxil CR for new indication

Staphylococcus Aureus - Inmate skin infections becoming a concern

Streptococcus - Mouse monoclonal antibodies for pneumolysin characterized

Stroke - Few people recognize warning signs

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