Proteomics
Proteins associated with inactive X chromosome reported
Published in Medical Letter on the CDC and FDA, November 16th, 2003
"The Barr body has long been recognized as the cytological manifestation of the inactive X chromosome (Xi) in interphase nuclei. Despite being known for over 50 years, relatively few components of the Barr body have been identified. In this study, we have screened over 30 histone variants, modified histones, and non-histone proteins for their association with or exclusion from the Barr body," scientists in the United States report.
"We demonstrate that, similar to the histone variant macroH2A, heterochromatin protein-1 (HP1), histone H1,...
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