Susan Hasty, Publisher
Table of Contents . . . December 21st, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications
Alcoholism - Many barriers exist to the use of medications for treating alcoholism
HIV/AIDS Therapy - HIV infection inhibited by cyclophilin from Toxoplasma gondii
Drug Development - Biopharmaceuticals becoming larger portion of drugs developed
Immunotherapy - Risks associated with use of intravenous immunoglobulin reviewed
Policy - Records link patients and disease for future policy implementation
Tobacco Use - Females especially susceptible to tobacco-related problems
AIDS Epidemiology - U.N.: Global AIDS epidemic rampant
AIDS Funding - Five-year, $1.5 million grant to fight spread of HIV/AIDS and TB in Africa
Acne - Company reports efficacy from phase IIb acne study
Allergy Medicine - Recent studies reduce need for pediatric studies of allergy medications
Angioedema - Icatibant gets orphan drug designation
Angioplasty - FDA updates information for physicians on Cypher stent
Antibiotics - Company updates timing of oritavancin NDA submission
Antimicrobial Resistance - Drug resistance linked to location and emm type of Streptococcus
Attention Deficit/Hyperactivity Disorder - ANDA filed for generic version of Adderall
Bacterial Contamination - Salmonellae can be concentrated from liquids by using an immunoaffinity column
Bioengineering - Mini-lambda presents a flexible system for in vivo genome engineering
Burn Medicine - Bacterial toxicosis contributes to morbidity in children with burns
Candidiasis - Vfend receives FDA approval for treatment of esophageal candidiasis
Cell Therapy - Tissue regeneration company shows positive results in the U.K.
Cholesterol - Ezetimibe acts as selective cholesterol absorption inhibitor
Contraception - FDA approves Ovcon 35 chewable birth control tablets
Contraception - FDA considers over-the-counter "morning after" pill
Contraception - New oral contraceptive marketed to healthcare providers
Corporate Update - Company provides overview of drug-eluting stent program
Correction - Supplement filed for approval of needleless device used with Kogenate FS
Dengue Fever - Dengue virus infects cells by viral envelope binding to polypeptides
Depression - Suicidal minority teens lack adult support
Dermatology - Approval granted for generic mometasone ointment
Diagnostics - HPLC method validated for determination of ranitidine in plasma
Disease Resistance - Scientists explore why most breastfed infants of HIV+ mothers resist infection
Environmental Toxins - New web site to screen for lead poisoning
Erectile Dysfunction - FDA approves third drug to treat ED
Esophageal Candidiasis - FDA approves Vfend for fungal infection
Food-borne Illness - Government report says salmonella declining in raw meat
Food-borne Illness - Report: Georgia, North Carolina hepatitis strains linked
Food-borne Illness - USDA announces unified food safety research agenda
Gastric Ulcer - Prevacid NapraPAC granted FDA approval
Generic Drugs - Filing for generic version of Adderall XR accepted by FDA
HIV Antibodies - Additional data submitted to FDA for oraquick HIV-2 claim
HIV Diagnosis - Pros and cons of HIV testing in less developed countries discussed
HIV Epidemiology - HIV transmission within the U.K. is increasing
HIV Epidemiology - New study shows overall increase in U.S. HIV diagnoses
Head Injury - Drug company stakes future on medicines from marijuana compounds
Heart Failure - Incara and Indevus outlicense bucindolol
Hematology - ABO blood type and race affects von Willebrand factor activity
Hives - FDA approves over-the-counter Claritin for hives treatment
Hypertension - Diorganotin(IV) complexes with captopril characterized
Infectious Disease - Serum albumin level linked to HFRS severity
Influenza - U.S. is poorly prepared for influenza pandemic, experts warn
Influenza - Worst flu season in 30 years predicted
Injury Prevention - Higher speed limits have translated to more deaths
Malaria Pathogenesis - Extracellular PSAC lysines involved in Na+ exclusion
Meningococcal Vaccine - Right decisions in public health based on science and expertise
Mental Health - High-cost Medicaid enrollees have more serious mental health disorders
Migraine Headache - FDA issues approvable letter for migraine prophylaxis indication for Topamax
Morphine Addiction - The GABA(B) receptor agonist baclofen inhibits opiate-induced reward effect
Multifunctional Receptors - Melanocortin 1 receptor is induced by alpha melanocyte stimulating hormone
Nosocomial Infection - Novel norovirus strain responsible for gastroenteritis outbreak in Swiss university hospital
Nosocomial Infection - Revised standards approved to prevent deadly healthcare-associated infections
Orthopedics - Volumetric CT evaluates therapy efficacy of peri-prosthetic osteolysis
Outbreaks - Contaminated fountain blamed for Pontiac fever outbreak in Tennessee
Parasitic Disease - Fascioliasis risk is high among women and schoolchildren in the Nile Delta
Pediatric AIDS - Children's genetic factors determine HIV progression
Pediatrics - School children in Cameroon harbor a variety of parasites
Policy - Group releases workforce report with new sense of urgency
Postoperative Pain - Pharmaceutical company seeks U.K. approval of DepoMorphine
Prion Disease - Therapies for transmissible spongiform encephalopathies reviewed
Prostate Cancer - FDA approves new drug for advanced prostate cancer
Proteomics - Schizosaccharomyces pombe Ras1 effector mediates cytokinesis
Proteomics - Clinical development of FGF-2 for therapeutic angiogenesis has limited success
Pseudomonas - FDA grants approval for Piperacillin injection
Regulatory Issues - Federal proposal alarms infertility community
Rheumatoid Arthritis - Costs calculated for arthritis, other rheumatoid diseases
Rheumatoid Arthritis - IND application filed for AME-527
SARS - China to test experimental vaccine
SARS - Dealing with emerging infectious diseases requires vigilance
Salmonella - orgC gene product of Salmonella enterica characterized
Smallpox - Company licenses technology from NIAID for vaccine for smallpox
Smoking Cessation - Study shows strong tobacco control programs and policies can lower smoking rates
Stents - Cobalt-alloy biliary stent now available in the United States
Syphilis - Screening for STD should be routine part of medical care for people with HIV
Syphilis - U.S. syphilis rate climbs for second consecutive year
Terrorism - $5M equipment order to help CDC improve response to terrorism
Tetanus - Gates Foundation gives $10 million to U.N. fight against deadly maternal tetanus
Toxoplasmosis - Complete cross-reactivity found in Toxoplasma gondii isolates
Transplant Medicine - Solitary pancreas transplant not associated with improved survival for diabetics
Trial Compliance - Med-eMonitor clinical trial data presented at FDA/Drug Information Association conference
West Nile Virus - Professor wins CDC grant to combat emerging infections
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