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Medical Letter on the CDC and FDA

Susan Hasty, Publisher

Table of Contents . . . December 28th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications

Hypertension - Dopamine and metabolite levels similar in three rat strains

Immunology - CpG oligonucleotides exhibit immunoregulatory activity in humans

HIV/AIDS Vaccine - Public health considerations for use of HIV vaccine outlined

Hematology - Metalloprotease expressed by Vibrio tubiashii characterized

Leishmaniasis - Leishmaniasis parasites identified in humans and dogs in eastern Sudan

AIDS Detection - Many heterosexual adults have not been tested for HIV

AIDS Funding - Global AIDS fund grants US$6.39 million for Zambia

AIDS Pandemic - $30M in new grants offered for African HIV/AIDS crisis

Accreditation - Study assesses prevention strategies in medical management and PPOs

Acne - FDA clears new acne laser treatment

Angina - Update provided on FDA review of revascularization system

Asthma - FDA approval granted for Aeroneb Go Nebulizer in home setting

Bacteriology -  Pasteurella multocida infection causes septicemia and arthritis in pigs

Bacteriology - Antibiotic use selects for resistant Moraxella catarrhalis strains

Breast Cancer - Better prognosis for HRT users more likely due to frequent screening

Breast Cancer - FDA clears new method for managing non-cancerous breast lumps

Cancer Therapy - Company announces phase I/II trial development of MDX-214

Cardiology - FDA approves new heart valve

Cardiology - FDA panel recommends approval for coronary stent system

Cardiovascular Procedures - Safe-Cross Total Occlusion Crossing System receives 510k peripheral clearance

Contraception - Culture may affect Hispanic women's use of birth control

Correction - Doctors announce first NIH-funded AIDS treatment research in Africa

Creutzfeldt-Jakob Disease - Transmission risk exists from dural graft implantation

DNA Damage - DNA damage plays role in genetic predisposition to arsenic cytotoxicity

DNA damage - Two distinct pathways exist for inhibiting Pds1 ubiquitination

Diabetes - Generic version of popular diabetes treatment launched

Diabetes Outcomes - Study finds pancreas transplants riskier than blood sugar control

Drug Screening - FDA updates and clarifies draft guidance on drugs of abuse screening tests

Environmental Toxins - Young males exposed to pesticide endosulfan see delay in sexual maturation

Fitness - Even more "couch potatoes" in Brazil than in U.S. - but they're starting to move

Food-borne Illness - Chi-Chi's outbreak raises questions about FDA's ability to screen

Food-borne Illness - Cooking ensures safe vegetables, CDC says

Food-borne Illness - Microplate sandwich assay suitable for detection of E. coli O157:H7 in food

Food-borne Illness - Process for value assignment of aflatoxin in peanut butter published

Forensics - DNA analysis company awarded FBI contracts to develop SNP technology

Gynecology - Newly approved microwave therapy is a 'significant advance' for menorrhagia

HIV - Gel received FDA fast-track designation for reduction of HIV transmission

HIV Epidemiology - Population surveys: New "gold standard" for estimating incidence of HIV/AIDS?

HIV Notification - Partner notification program successfully identifies new HIV cases

HIV/AIDS Tuberculosis - Chest radiography has limited value in HIV-TB diagnosis

Heart Failure - FDA gives approval to market TLC-II for home discharge

Hemodialysis - Icodextrin fulfills unmet clinical need of peritoneal dialysis patients

Hepatitis A - Restaurant comments on developments in investigation of outbreak

Hypertension - Endothelin receptor blockers find use for hypertension treatment

Infection Control - Disinfection of flexible nasopharyngoscopes lacking in South Africa

Infection Control - Suggestions to reduce urological infections after surgery published

Injury Prevention - Variations in state laws affect elder abuse documentation

Leishmaniasis -  Leishmania major secreting GM-CSF delays disease development in mice

Lung Disease - FDA approves new treatment for chronic bronchitis

Menopausal Symptoms - FDA approves Climara Pro transdermal system

New Products - NewsRx expands to 100 titles in Health Law and Business

Nicotine Addiction - Sixth-graders' intentions are first steps on road to smoking

Nosocomial Infections - Enrollment complete for phase II Veronate trial

Obesity Prevention - NIH workshop outlines pathways to obesity prevention

Occupational Health - Benzo[a]pyrene acts as molecular biomarker of asphalt fume exposure

Oncology - Study data presented on agent for malignant glioma

Ophthalmology - Early treatment of retinopathy in infants can prevent severe vision loss

Ophthalmology - New drug may help treat macular degeneration

Orthopedics - FDA clears new implant for rotator cuff injuries

Pediatric AIDS - Why do most breastfed infants of HIV-positive moms resist infection?

Pertussis - Incidence of pertussis among infants appears to be increasing

Policy - Editorial calls for outright smoking ban in U.K.

Product Management - Accelerator for FDA Compliance, a PLM solution for device market, launched

Reimbursement - HealthBridge to manage Ganite maker's patient assistance program

Rheumatoid Arthritis - Lung involvement in rheumatoid arthritis reviewed

Rotavirus - N- and C-terminal regions of rotavirus critical for viroplasm formation

SARS - Animal model shows early promise for SARS vaccine

SARS - Better tests needed for diagnosis

SARS - Communication is key to successful U.S. quarantine

Smallpox Vaccine - Guidelines for managing smallpox vaccination complications outlined

T Cell Function - Strength and persistence of antigen stimulation will alter T cell responses

Thyroid - Parathyroid hormone measurement requires correct specimen preparation

Transplant Medicine - Industry working to improve safety of donated tissue

Vaccine Development - Functionalized carbon nanotubes enhance specific antibody responses

Vaccine Development - Partnership announced for the development of an Ebola vaccine

Varicella-Zoster Virus - PCR assay developed for detection of varicella-zoster virus DNA

West Nile Virus - Few WNV-infected animals found in Austria

West Nile Virus - Scientists get images of West Nile pathogen

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