Creutzfeldt-Jakob Disease

Transmission risk exists from dural graft implantation

Published in Medical Letter on the CDC and FDA, December 28th, 2003

Creutzfeldt-Jakob Disease (CJD) needs to be considered in people developing rapidly progressive dementia, particularly if there is a history of dural graft implantation or other neurosurgical procedure, according to a new report appearing in the U.S. Centers for Disease Control and Prevention's (CDC) Morbidity and Mortality Weekly Report.

CJD is a rapidly progressive, fatal dementing illness that may rarely be transmitted through direct inoculation of the central nervous system (CNS) with infected material. Cases worldwide have occurred from receipt of improperly treated dura mater harvested from CJD patients and used in neurosurgical procedures; the majority of...

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Source: Medical Letter on the CDC and FDA (2003-12-28)

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