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Medical Letter on the CDC and FDA

Susan Hasty, Publisher

Table of Contents . . . January 25th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications

Anthrax - Anthrax mounts nuclear attack on glucocorticoid signaling

Anthrax - Calcium may play role in folding pathway of anthrax protective antigen

Anthrax - FDA clears lab culture test for anthrax

Anthrax - FDA issues final order on safety of bacterial vaccines and toxoids

Anthrax Vaccine - Flow cytometric assay for responses to anthrax vaccine developed

Anti-Infectives - FDA approves manufacturing and marketing of Cefaclor Tablets, Chewable

Antifungals - Terbinafine HCl Tablets receives tentative FDA approval

Awards - Thompson honored for his contributions to medicine, public health

Behavioral Medicine - Factors affecting validity of self-reports among adolescents determined

Bovine Spongiform Encephalopathy - FDA issues statement on new measures against BSE

Bovine Spongiform Encephalopathy - FDA issues statement on rendered products derived from BSE cow in Washington

HIV/AIDS Therapy - LC-MS method for measuring zidovudine and lamivudine in mice developed

Brain Injury - Depression, other psychiatric illnesses common following brain injury

Cancer Mortality - Researchers report cancer incidence and mortality in the Netherlands

Cancer Prevention - College receives $10 million for cancer prevention trials

Cardiovascular Risk - Trial studies best ways to prevent heart problems in type 2 diabetes patients

Clinical Trials - Update released on investigational device exemption for drug stent

Complementary and Alternative Medicine - U.S. bans ephedra, drug linked to deaths

Depression - Research reveals social isolation boosts teen girls' suicide thoughts

Diagnostics - FDA approves molecular diagnostic test for sexually transmitted diseases

Drug Abuse - Survey shows decline in teen drug abuse over past 2 years

Environmental Health - Rice strains genetically engineered for mercury resistance may clean water

Botulinum Toxin - Electrophoresis method to evaluate botulinum toxin activity developed

Fitness - Full-bodied models highlight fitness ads

Fitness - Increased physical activity called priority for Americas

Food Supply Safety - FDA and CBP announce their transitional compliance policy on food imports

Funding - Public-private collaboration to target new treatments for depression, nicotine addiction

Gonorrhea - Louisiana has worst gonorrhea rate, in top 10 in two other STDs

Gout - New drug application submitted for Oxyprim

HIV Diagnosis - FDA OKs U.S. sale of 10-minute HIV test

HIV Epidemiology - Name-based reporting leads to better information in New York City

HIV Testing - Uni-Gold Recombigen HIV test receives FDA approval

HIV Therapy - Best treatment for new HIV patients to be studied

Drug Development - Numbers of fish used in acute ecotoxicity testing of pharmaceuticals reduced

HIV/AIDS Epidemiology - HIV-1 seroprevalence rates in women and relinquishment of infants to the state in Russia

HIV/AIDS Vaccine - Antigen engineering promotes induction of HIV-neutralizing antibodies

Health Statistics - Teen birthrate drops 7% in Arkansas

Hepatitis B Vaccine - Immunity persists 4 years after hepatitis B vaccination

Hepatitis B Virus - Rates on the decline in the United States but not among adults

Hepatitis B Virus - Study will compare two antivirals for lamivudine-resistant disease

Hormone Replacement Therapy - FDA teams up with women's health organizations to raise awareness about HRT

Immunology - Phagocytosis accelerates maturation of polymorphonuclear leukocytes

Influenza - Flu outbreak tests new federal law limiting release of medical information

Influenza - Officials hope break brings flu downturn

Food Supplements - NMR used to quantify ephedrine analogues from Ephedra species

Klebsiella -  Klebsiella oxytoca harbors carbapenem-hydrolyzing beta-lactamase KPC-2

Leg Ulcers - Premarket approval application to be filed for venous leg ulcer treatment

Legal Issues - Biotech patent dispute settled

Measles Vaccine - ELISA and virus neutralization assay yield same measles antibody titers

Medical News - Harvard rates top 10 health/medical stories of 2003

Mental Health - FDA approves medication for bipolar depression

Mosquito-borne Disease - Marsupials help prevent establishment of Japanese encephalitis in Australia

Myelodysplasia - Study looks at immune-suppressing treatments

Myelodysplastic Syndrome - New drug application submitted to market myelodysplastic syndromes therapy

Myelodysplastic Syndrome - Trial will compare Daclizumab to ATG to treat the cytopenia of myelodysplastic syndrome

Salmonellosis - U.S. outbreak of Salmonella enterica linked to mango consumption

Myocardial Infarction - Company seeks new drug indication for treatment of heart attack survivors

Nearsightedness - Review date set for phakic intraocular lens premarket approval application

Norovirus - CDC: Nearly 65 passengers on cruise ship get stomach illness

Obesity Diagnosis - Screening recommendations for obesity in adults released

Ophthalmology - FDA issues approval letter for dry eye treatment

Osteoporosis - ANDA submitted for hormonal nasal spray that may combat osteoporosis

Outbreaks - Enrichment culture could aid laboratory detection of C. perfringens

Outbreaks - Rate and severity of serogroup X meningococcal meningitis in Niger clarified

Pain Management - FDA approves generic oxycontin

Parkinson Disease - Alpha-synuclein interacting protein gene and Parkinson disease studied

AIDS Epidemiology - American Indians see rapidly climbing AIDS infection rates

Pediatric AIDS - More effective prenatal care could halt perinatal transmission of AIDS

Pediatric Obesity - Panel set to rid Florida schools of junk food

Pediatric Obesity - U.S. has highest prevalence of overweight teens in 15-country study

Pediatrics - Strategies for assessing child neglect reported

Pediatrics - U.S. CDC releases annual summary of pediatric vital statistics for 2002

Perinatal HIV - Rapid HIV tests for women in labor studied

Policy - Mozambique: U.N. human rights expert decries discrimination against AIDS patients

Prion Disease - Helix 1 peptide elicits antibodies against prion protein in mice

Rabies - Disease remains a costly public health threat, says virologist

Respiratory Syncytial Virus - Palivizumab and RSV-IGIV indications for respiratory syncytial virus revised

Acne - New drug application submitted for Actiza

SARS - Severe acute respiratory syndrome -associated coronavirus vaccine shows promise in monkeys

SARS - WHO wants China's suspected SARS case tested overseas

Smallpox - Researchers intrigued by century-old smallpox scabs

T-Cell Function - Venezuelan EEV replicons increase CD56+ T cells with NK-like activity

Thrombosis - FDA approves lab tests for genetic clotting risk

Thrombus - Pronto extraction catheter receives 510(k) clearance from FDA

Toxicology - "Homegrown" relief may aid victims of arsenic poisoning in South Asia

Trypanosomiasis - Diagnosing sleeping sickness outside Africa is difficult

Tuberculosis -  M. tuberculosis ethA and inhA gene mutations linked to ethionamide resistance

Tuberculosis Therapy - CDC study will compare short versus long-term TB treatment regimens

Angina - U.S. Food and Drug Administration advisory committee evaluates Ranexa

Vaccines - Investigational new drug application to be filed for HIV vaccine

Varicella Vaccine - Incidence of herpes zoster in children reported

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