Anthrax
Anthrax mounts nuclear attack on glucocorticoid signaling
Published in Medical Letter on the CDC and FDA, January 25th, 2004
According to recent research from the United States, "Anthrax causes profound inflammation and systemic shock. A recent study has shown that anthrax lethal toxin represses the transcriptional activity of the glucocorticoid receptor, which is a crucial component of the body's defenses against inflammation. The study reports evidence that lethal toxin blocks the glucocorticoid receptor by inhibiting the p38 mitogen-activated protein kinase pathway."
"Thus, these findings suggest that glucocorticoid receptor inactivation contributes to anthrax toxicity and raise the possibility of developing...
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