Susan Hasty, Publisher
Table of Contents . . . February 15th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications
Meningitis - Echovirus type 13 emerging as prominent enterovirus
Adolescent Health - Survey finds 8,000 clandestine abortions occur yearly in Burkina Faso capital
Alzheimer Disease - Namenda now available nationwide
Amyotrophic Lateral Sclerosis - AEOL 10150 clears toxicology hurdle; company makes initial draw on financing
Animal Models - Diets with different levels of soy affect toxicity assessments in rats
Anticancer Therapy - Recent developments in antitumor taxoids reviewed
Avian Influenza - Vietnam last on vaccine list
Avian Influenza - WHO says SARS helped Asia on bird flu
Avian Influenza - WHO suggests quarantine for bird flu
Bacteriology - Accuracy of six systems for Vibrionaceae identification compared
Tularemia - PCR assay for enhanced detection of Francisella tularensis developed
Baylisascaris - Baylisascaris procyonis found in metropolitan Atlanta area
Biosample Archiving - BioServices division wins contract to establish NIDDK biosample repository
Bipolar Disorder - FDA approves Zyprexa to delay relapse into mania, depression
Bipolar Mania - FDA grants approval for Seroquel
Bone Cancer - Orthopedic implant designed to restore function
Botulinum Toxin - Hemagglutinin element of toxin from Clostridium botulinum identified
Breast Cancer - FDA grants clearance to market Ariol HerSight
Cancer Therapy - CRADA inked for pancreatic, ovarian, and lung cancer antibody development
Chemotherapy - Helsinn signs licensing agreement for palonosetron with Japanese firm
Clinical Trials - Proper metrics for clinical trials outlined
Food-borne Illness - Rugged LC-MS/MS survey analysis developed for acrylamide in foods
Cochlear Implants - Penetrating electrode auditory device successfully implanted
Collaborations - Biopharmaceutical company enters joint SARS clinical program with Vanderbilt
Collaborations - M&H Informatics enters agreement to provide packaging solution
Collaborations - Pharmaceutical company identifies SARS antisense drug candidates
Colon Cancer - Eloxatin approved in U.S. for treatment of metastatic colorectal cancer
Colon Cleaning - Phase II study to begin on new purgative product
Colorectal Cancer - Tumor-related Rac1b not regulated by Rho-GDP dissociation inhibitors
Coronary Artery Bypass - Veterans' healthcare agency has more care problems than private sector hospitals
Dermatology - FDA clears phototherapy technology developed in Israel
Diabetes Pathogenesis - Insulin resistance found in offspring of rats using alcohol while pregnant
Melanoma - Canvaxin therapeutic polyvalent vaccine shows promise against melanoma
Drug Approvals - FDA grants approval for generic contraceptive, manic disorder drug
Drug Costs - FDA says U.S. generics a better bargain than many Canadian drugs
Drug Development - FDA approves generic drug manufacturer based in India
Drug Development - Report: FDA will be pressed to do more with less
Drug Development - UMass medicine hunter tracks plants with healing promise
Enterococcus - Glycopeptide-resistant Enterococcus faecium found in ICU
Environmental Health - Method for dual measurement of urinary bisphenol A and alkylphenols developed
Ephedra - Methods of addressing potential risks associated with ephedra use reviewed
Epilepsy - Expanded indication for Lamictal offers additional treatment options
Fabry Disease - Biopharmaceutical company to ceases to seek U.S. approval of Replagal
Outbreaks - Vibrio cholerae outbreak linked use of chlorinated water source
Food-borne Illness - Main bacteria contributing to histamine formation in seafood identified
Food-borne Illness - Results from viral monitoring of oysters in polluted estuary reported
HIV/AIDS Pathogenesis - Serum SDF-1 inactivated during HIV infection
HIV/AIDS Prevention - Incorporating HIV prevention into the medical care of persons living with HIV
HIV/AIDS Risk Factor - Transmission risk data lacking in HIV/AIDS surveillance system
HIV/AIDS Vaccine - Multispecific mucosal cytotoxic T cells fail to control SIVmac239
Heart Attack - NIH grant awarded to study the use of adipose-derived regenerative cells
Hepatitis E Vaccine - HEV-neutralizing antibodies recognize antigen of ORF2 protein vaccine
Hereditary Angioedema - Positive phase II study results with Icatibant
Human Papillomavirus - Women's Health Connecticut adopts DNAwithPap test
Weight Gain - Adolescents tend to gain excessive weight during pregnancy
Influenza - Flu continues to decline; just five states now reporting widespread illness
Information Technology - CMS strengthens initiatives with clinical evidence-based criteria
Legal Issues - Makers of OxyContin made unsubstantiated claims, report says
Legionnaires Disease - Type I secretion system in Legionella pneumophila described
Limb Ischemia - Treatment for critical limb ischemia submitted to FDA
Malaria Therapy - Trends in antimalarial drug deployment in sub-Saharan Africa reported
Mergers and Acquisitions - FTC closes review of Novazyme acquisition
Mycobacteria - Clinical management of Mycobacterium fortuitum skin infection outlined
Mycology - Antigens shared by Aspergillus and Penicillium species identified
Obesity - CDC: Obesity costs states billions in medical expenses
AIDS Therapy - IND application filed for protease inhibitor GS 9005
Obesity Prevention - Governments back WHO's anti-obesity plan
Osteoporosis - New phase III study shows positive results for oral monthly Boniva
Pain Medicine - FDA launches consumer campaign on safe use of OTC pain products
Panic Disorder - Emotion-regulating protein lacking in panic patients
Patents - Geron receives favorable ruling in nuclear transfer patent interference matter
Pediatrics - Development of rational therapeutics in children reviewed
Poliomyelitis - WHO considers rapid response to halt polio spread in Africa
Prescription Drug Abuse - Petition requests FDA to require risk management plans for OxyContin generics
Prescription Drug Importation - FDA scrutinizing county's plan to bring in drugs from Canada
Prescription Drug Importation - Iowa governor seeks HHS authorization for pilot program
AIDS and HIV - Gene product restricts HIV-1 replication in resting CD4+ lymphocytes
Product Safety - U.S. regulators uphold ban on silicone gel breast implants to market
Rabies Virus - Novel lyssaviruses isolated from bats in Russia
Regulatory Issues - FDA implements broader requirements for tissue bank registration
Regulatory Issues - FDA sees rebound in approval of innovative drugs in 2003
Regulatory Issues - FDA takes actions against illegal drug import operations
Renal Cell Cancer - Interim clinical results of GTI-2040 in combination chemotherapy announced
Robotics - Robotic mitral valve surgery reviewed
SARS - Flu season helps U.S. prepare for SARS
SARS - WHO finds evidence that animals play SARS role
Salmonella - Salmonella enterica isolated from humans and food animals characterized
Adolescent Health - New reproductive health program informs girls in Nairobi slums
Schistosomiasis - IL-10 regulates immune responses induced by schistosome vaccine
Seborrheic Dermatitis - Results reported from phase III studies of Sebazole
Smallpox - Smallpox vaccines to be delivered to CDC
Streptococcus - Researchers map pneumococcal surface protein A of strain Rx1
TB Prevention - WHO launches program to curb TB/HIV co-infection
Urology - Bladder screening device approved in U.S.
Veterans Affairs - Group is suing Veterans Affairs' secretary over "rationing" of healthcare services
West Nile Virus - CDC: 2003 West Nile outbreak largest yet
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