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Medical Letter on the CDC and FDA

Susan Hasty, Publisher

Table of Contents . . . February 22nd, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications

Cryptosporidium - Glycolipid antigen from Cryptosporidium parvum characterized

Antifungal Drugs - FDA reports 90-day extension of anidulafungin new drug application review

Avian Influenza - Asia nations seek to keep bird flu at bay

Avian Influenza - CDC: Bird flu could come from abroad

Avian Influenza - WHO: Chances good for beating bird flu

Biliary Obstructions - New biliary stent system launched in U.S.

Bladder Screening - FDA issues marketing approval for Portascan

Blood Pump - FDA grants 510(k) clearance for miniature blood pump

Chlamydia - Developments in screening for Chlamydia trachomatis reviewed

Cholera - Positive results of cholera vaccine trial in Bangladesh reported

Collaborations - Neurogen agreement for next-generation pain drugs consummated

Prion Disease - Vaccines against prion diseases may be in sight

Colon Cancer - Eloxatin submitted in U.S., Europe as adjuvant treatment

Complementary and Alternative Medicine - NIH Office of Dietary Supplements releases new 5-year strategic plan

Creutzfeldt-Jakob Disease - Expanded "mad cow" safeguards announced to strengthen existing firewalls

Cryptosporidiosis - CDC report: Health authorities should have warned of parasite

DNA Microarray - False discovery rates in gene microarray data estimated

DNA Research - Thermolytic 5'-hydroxyl protection of deoxyribonucleosides developed

DNA Research - Thermolytic protecting groups for oligodeoxyribonucleotides reported

Depression - FDA weighs antidepressant risk to kids

Dermatology - Topical immunomodulators used to treat atopic and eczematous dermatitis

Domestic Violence - Cultural, economic factors fuel rise in abuse of women in Zimbabwe

Adverse Drug Effect - Effect of d-fenfluramine on platelet serotonin uptake described

Drug Development - Company meets with FDA on MBI-226

Ebola Virus - Republic of Congo declares end to latest Ebola outbreak; 29 dead

Endocrinology - Progesterone levels sway uterine capacity and conceptus formation in pregnancy

Escherichia Coli - Outbreak of Shiga toxin-producing E. coli O111:H8 reported

Finance - Biomaterials company announces EPS of $0.23 for second quarter, up 44%

Finance - Company reports fourth quarter EPS up 34.8%; 2003 EPS up 11.1%

Finance - Developmental stage biopharmaceutical completes private placement

Finance - INEX makes milestone payment to former partner

Food Safety - Residue depletion of albendazole in trout and salmon studied

Food-Borne Illness - Volatile organic compounds found in foods

Malaria - Methods estimate infectiousness of P. vivax carriers to mosquitoes

Generics - FDA approves 25-mg metoprolol tartrate

HIV/AIDS - In Mozambique, stigma remains obstacle to treatment for HIV+ women

HIV/AIDS Vaccine - Broadly cross-reactive HIV-neutralizing antibody Fab identified

Heart Disease - FDA approves Internet access to cardiac home monitoring system

Hydrocephalus - Transgene related to development of congenital hydrocephalus

Immunology - Autoubiquitylation of the V(D)J recombinase protein RAG1 reported

Implants - PIP subsidiary wins European approval of new manufacturing process for implants

Leukemia - FDA approval granted for liquid form of cytarabine injection

Lung Cancer - "Rolling" NDA submission initiated for Tarceva

Malaria Vaccine - Malaria immunity linked to circumsporozoite protein-specific T cells

Transfusion Medicine - Recommendations for managing recalls of blood components released

Malignant Neoplasms - Zilver 518 biliary stent launched following FDA approval

Maternal Mortality - U.S. establishes new center for pregnant women in Angola

Medicare - Medicare payment updates, policy changes proposed for long-term care hospitals

Medicare - Payments to Medicare HMOs to increase by 10.6%

Melanoma - Active-specific immunization against melanoma reviewed

Nicotine Addiction - Report presents snapshot of national smoking habits

Obesity - American taxes pay for most obesity health ills according to study

Obesity - U.N. health agency's antiobesity plan gets the nod from several governments

Obesity - U.N. report on obesity challenged by the United States

Occupational Health - Bradley-Terry-Luce method applied to person-environment (P-E) fit

Tuberculosis - Recent advances in lab procedures for pathogenic mycobacteria reviewed

Ophthalmology - National plan for eye and vision research released

Parkinson Disease - FDA approves brain pacemaker

Pediatric Obesity - Body mass index calculcator especially for kids developed

Preterm Labor - Fetal fibronectin and salivary estriol can predict preterm labor

Public Health - Medicaid managed care in New Mexico associated with decreased vaccination rates

Quality Assessment - Medicare releases enhanced set of nursing home quality measures

Rabies Vaccine - Batch of rabies vaccine found ineffective

Rheumatoid Arthritis - tgAAC94 to undergo rheumatoid arthritis clinical trial

Salmonella - Limited boundaries exist for gene transfer among Salmonella pathogens

Schistosomiasis Vaccine - Development on schistosomiasis vaccines stalled

Acute Bacterial Sinusitis - FDA approves Zithromax as treatment for acute bacterial sinusitis

Sexual Violence - Advocacy group says attacks against women, girls rising in northern Uganda

Sleep Disorders - FDA approves drug to help people with shift-work or obstructive apnea disorders

Tissue Banking - Fertility clinics, sperm banks must register with FDA

Tuberculosis Vaccine - T cells recognize epitopes of Mycobacterium tuberculosis antigen

Vectors and Zoonoses - Variant strain of Anaplasma phagocytophilum unable to infect mice

West Nile Virus - WNV antibodies found in New Jersey black bears

Wound Care - INDERMIL Tissue Adhesive receives FDA approval as a microbial barrier

Anthrax - Anthrax vaccine candidate receives fast track designation

Antibiotics - Analysis of antibiotics by capillary electrophoresis reviewed

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