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Vectors and Zoonoses

Variant strain of Anaplasma phagocytophilum unable to infect mice

Published in Medical Letter on the CDC and FDA, February 22nd, 2004

A variant strain of Anaplasma phagocytophilum was unable to infect mice.

According to recent research published in the Journal of Infectious Diseases, "Nymphal Ixodes scapularis ticks were collected from several sites in Rhode Island. Polymerase chain reaction and DNA sequencing were used to determine the presence and prevalence of Anaplasma phagocytophilum human agent (AP-ha) and a genetic variant not associated with human disease (AP-variant 1). The remaining ticks from each cohort were allowed to feed to repletion on either white-footed (Peromyscus leucopus) or DBA/2 (Mus musculus) mice."

"The engorged...

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