Antimicrobials

Antimicrobials isolated from Salvia and Eucalyptus species

Published in Medical Letter on the CDC and FDA, February 29th, 2004

According to a study from Russia, "The mechanism of action of quinones from the roots of Salvia officinalis L. (royleanones) and terpenoid phenolahlehydes from the leaves of Eucalyptus viminalis Labill. (euvimals) was studied."

"Royleanones and euvimals displayed marked protonophoric activity on artificial bilayer lipid membranes in vitro, and exerted an uncoupling action on oxidative phosphorylation in isolated rat liver mitochondria," reported Nikolay A. Spiridonov and colleagues at the Russian Academy of Sciences. "The results suggest that biological membranes are the primary targets of royleanones and euvimals, and the protonophoric activity may...

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Source: Medical Letter on the CDC and FDA (2004-02-29)

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