Susan Hasty, Publisher
Table of Contents . . . March 14th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications
Hepatitis E Vaccine - Hepatitis E virus DNA vaccine protected cynomolgus macaques against infection
Poliomyelitis Vaccine - Vaccine-derived polioviruses decline in patients with poliomyelitis
Botulinum Toxin - Mouse bioassay and ELISA compared for detecting botulinum toxin in food
Breast Cancer Risk Factor - Adipose PCB increases risk of breast cancer recurrence in women
Food-borne Illness - Putrescine indicates decomposition in penaeid shrimp
Salmonella - Assay for detecting salmonella in water used for sprout seeds developed
Alcohol Abuse - Five million parents have alcohol problems, federal report says
Amyloidosis - FDA grants fast track approval for Fibrillex
Anesthesia - FDA issues clearance of next generation anesthesia monitor
Anthrax - Surface layer protein EA1 is not component of Bacillus anthracis spores
Avian Influenza - Bird flu not going away soon, WHO says
Avian Influenza - Infection-control company launches fight against avian flu
Avian Influenza - New research could lead to potential treatment for avian flu
Avian Influenza - South Asia health officials hold emergency meeting on avian influenza
Avian Influenza - U.S. senators want task force to deal with avian flu
Avian Influenza - Vaccine could be made quickly if Asian bird flu goes global, U.S. officials say
Bacillus Calmette-Guerin Vaccine - Intranasal BCG vaccine better than subcutaneous vaccine against pulmonary TB
Bovine Spongiform Encephalopathy - Researchers search for new mad cow test
Business & Finance - Trospium maker reports net loss for first quarter 2004
Cancer Therapy - Salvinal has antimitotic activity in drug-resistant human tumor cells
Catheter-Related Infections - U.S. Food and Drug Administration approves clinical trial for MethLock
Childhood Immunization - Parents must get more information to counter immunization fears
Chlamydia - Disease incidence set North Dakota record in 2003
Chronic Beryllium Disease - Electrostatics affect antigen recognition in chronic beryllium disease
Colon Cancer - Gender and location may be related to the pathogenesis of colon cancer
Complementary and Alternative Medicine - FDA approves acupressure wristband for nausea
Complementary and Alternative Medicine - Regulatory issues on safety and efficacy of herbal remedies discussed
Contraception - Bush advocates abstinence-only education
Contraception - FDA postpones morning-after pill decision
Contraception - Survey shows slow start for California's new "pharmacy access" program
Cysticercosis - Taenia solium antigen diagnostic for cysticercosis characterized
Dengue Fever - Dengue virus strains show promise for candidate vaccines
Dengue Fever - Factors affecting vector competence of dengue virus mosquitoes studied
Dengue Fever - Live-attenuated dengue virus vaccine stimulates TH1 immune responses
Dengue Fever - Safe and immunogenic monovalent attenuated dengue vaccines developed
Dengue Virus - Dengue virus envelope protein changes structure after membrane fusion
Diabetes Management - FDA approves new Guardian Continuous Glucose Monitoring System
Dialysis - FDA clears SpeedLyser infusion catheter
Diet and Nutrition - Breastfeeding longer is beneficial
Disease Prevention - Aging CDC labs will be improved with appropriation of $250 million
Disease Prevention - Federal panel recommends increased mad cow testing
Drug Delivery - ANDA filed for Toprol-XL; generic version of Lotensin launched
Drug Safety - Group joins FDA effort to ensure integrity of drug supply
Ebola Virus - Ebola virus-like particles protect from lethal Ebola virus infection
Ebola Virus - Infection with Ebola virus persists under conditions of partial immunity
Epidemiology - Leukemia panel will meet once more in northern Nevada town
Finance - Diagnostics company reports strong financial results for Q4 and full year 2003
Food-borne Illness - Yersinia pseudotuberculosis traced to fresh produce for the first time
Food-borne Illness - Effects of handling on biogenic amine formation in fish reported
Generic Drugs - Company announces approval and launch of benazepril hydrochloride tablets
Generic Drugs - FDA approves Benazepril Hydrochloride ANDA
HIV/AIDS Pathogenesis - Immune failure occurs without CD4+ T-cell depletion in SIV-infected macaques
HIV/AIDS Transmission - Heterosexual Hispanics, blacks account for high proportion of cases
HIV/AIDS Treatemnt - Human clinical trials of HIV maturation inhibitor to commence
Heart Disease - FDA requests additional information on decellularized heart valves
Heart Disease Risk - More needs to be done to fight heart disease in young people
Hypertension - Benazepril Hydrochloride Tablets approved for marketing
Hypertension - Company receives final approval on benazepril HCl/HCTZ tablets
Hypertension - FDA plans expedited evaluation of AmVaz NDA
Immunizations - A-Fujian strain tentatively added to influenza vaccine for next year
Immunizations - Campaign launched to immunize against Africa polio outbreak
Immunology - FDA grants orphan drug designation for Altastaph
Infectious Disease - Medical examiner database useful for fatal infectious disease surveillance
Influenza - Flu vaccine's results leave experts uncertain of next season preparations
Influenza - Report finds inactivated influenza virus vaccines effective in children
Influenza - WHO adds Fujian flu to vaccine list for next winter
Influenza Vaccine - Benefit of new influenza vaccine in healthy children investigated
Influenza Vaccine - Signed consent requirement for influenza vaccination should be eliminated
Insomnia - FDA allows IND for extended-release formulation of Sonata
Legal Issues - Federal appeals court upholds dismissal of Zoloft lawsuit
Leukemia - Generic Purinethol tablets receive marketing clearance
Malaria Vaccine - Polymorphism reducing P. falciparum rosetting protects against malaria
Maternal Mortality - WHO: More effort needed to cut the half-million annual deaths in childbirth
Medical Malpractice - U.S. Treasury secretary calls for lawsuit damage cap
Meningitis - Health groups recommend temporary suspension of pediatric vaccine dose
Menopause - FDA approves EstroGel transdermal gel for estrogen therapy
Mergers and Acquisitions - Acquisition gives Nanogen foothold in point-of-care diagnostics market
Mycobacterium - Luminex profiling system applied to M. tuberculosis genotyping
Nutrition - Government computerizes calorie plan
Nutrition - Wild Oats Markets removes all products containing hydrogenated oils
Obstetrics - Number of cesarean deliveries in Pennsylvania continue to rise
Ophthalmic Antibiotic - FDA approves Neomycin, Polymyxin B Sulfates, Bacitracin Zinc ophthalmic ointment
Osteoporosis - Hormone found to protect bones
Pediatric Obesity - National campaign to get kids physically active is working
Peripheral Artery Disease - IND Application filed for peripheral artery disease therapy
Personnel - Mozambique premier to take up research post at U.N. health agency
Presbyopia - FDA panel recommends approval of CK System for near vision improvement
Quality Assurance - Respiratory products manufacturer receives FDA warning letter
Respiratory Medicine - Two formulations of ambroxol hydrochloride tablets are bioequivalent
Smallpox - Few cases of vaccinia transfer reported
Study Ethics - Unusual study tests artificial blood without patients' consent
Systemic Lupus Erythematosus - Enrollment complete in confirmatory phase III clinical trial of Prestara
Tick-borne Encephalitis - Widespread immunization reduces incidence of tick-borne encephalitis
Toxicogenomics - FDA supporting toxicogenomic research through ArrayTrack
Vaccinia Virus - Protein kinase has essential catalytic role in vaccinia virus morphogenesis
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