Susan Hasty, Publisher
Table of Contents . . . March 21st, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications
Anthrax - New assay better than ELISA for measuring antibodies to anthrax toxins
HIV/AIDS Diagnosis - New automated ELISA reduces detection time of HIV-specific antibodies
Meningitis - Slide agglutination discrepancies resolved in Neisseria meningitidis
Mycobacterium - Mycobacterium vanbaalenii PYR-1 degrades benzo[a]pyrene
Preventive Medicine - Practical and regulatory issues in prevention studies outlined
Rabies Virus - Detection of rabies virus by PCR difficult due to virus heterogeneity
Achondroplasia - Defective lysosomal targeting of FGFR3 leads to achondroplasia
Alzheimer Disease - Evaluation of disease-modifying therapies in Alzheimer disease reviewed
Antimicrobials - Extension of NCCLS guidelines is not warranted
Aortic Aneurysm - PMA accepted by FDA for stent graft
Autoimmune Disease - Light chain-expressing B cells produce self-reactive antibodies
Avian Influenza - WHO says bird flu in house cats unlikely to increase risk of human risk
Behavior - Adolescent brains show reduced reward anticipation
Biotechnology - U.S. calls European fears over biotech crops an "overreaction"
Botulinum Toxin - Uptake of botulinum neurotoxin into cultured neurons explored
Business & Finance - Cancer therapeutics company reports fourth quarter and full year 2003 results
Business & Finance - Generics maker reports revenue increases, files eight new INDs/ANDAs in 2003
Business & Finance - Q2 revenues up 9% over same quarter last year for ion-technology company
Cancer Therapy - IND application filed for anticancer agent XL647
Canker Sores - OraDiscA NDA accepted for FDA filing
Colon Cancer - Erbitux receives FDA approval
Colon Cancer - FDA approval granted for EGFR pharmDx
Contraception - FDA extends Plan B emergency contraceptive PDUFA date
Correctional Healthcare - Elderly inmates swell U.S. prisons, driving up healthcare costs
Counterfeit Prevention - New RFID inventory solution meets FDA anticounterfeiting recommendations
Dengue Fever - Hematocrit, platelet levels do not predict shock in children
Diarrhea - FDA grants fast-track status Ramoplanin
Drug Development - FDA agrees to manufacturing plans for ISA247
Enlarged Prostate - FDA approval granted for Prolieve Thermodilatation system
Exercise - American youth more physically active, survey shows
Facilities - CDC granted $250 million appropriation to improve aging labs
Generic Drugs - FDA approves ANDA for generic glyburide/metformin HCl
HIV/AIDS Funding - Bush unveils emergency plan in fight against AIDS
HIV/AIDS Prevention - AIDS threat growing throughout Europe
HIV/AIDS Treatment - "Universal access" to HIV/AIDS treatment pledged by Europe, Central Asia
HIV/AIDS Treatment - Studies: Potential for Invirase plus ritonavir and protease inhibitors
Haemophilus - Metabolic indicator used to measure Haemophilus influenzae activity
Healthcare Coverage - U.S. HHS commissioner hasn't given up hope on drug pooling plan
Healthcare Disparities - U.S. HHS issues unedited version of earlier disparities report
Hearing Aids - VA awards contract to provide hearing care services in Florida, Georgia, Texas
Hemolytic Disease - FDA approves Rhophylac for prevention of hemolytic disease
Hepatology - Hepatopulmonary syndrome is concern for the anesthetist
Hormone Replacement Therapy - Scientists raise caution about effects of HRT on hearing
Infant Mortality - Iraqi healthcare effort to focus on infant mortality
Infectious Diseases - Tubercin testing continues at University of Colorado's Health Science Center
Influenza - Flu season is seen as moderately severe
Influenza - Influenza epidemics in France and United States follow similar patterns
Information Technology - NICHD selects Booz Allen Hamilton to support National Children's Study
Kidney Damage - FDA clears FlowMedica Bifurcated Infusion System for marketing
Knowledge, Attitudes, and Behaviors - Americans still don't get it when it comes to health, survey shows
Measles Vaccine - Edmonston-Zagreb measles vaccine induces cellular and humoral immunity
Meningococcal Vaccine - Neisseria meningitidis IgG concentrations assigned to reference sera
Multiple Sclerosis - Antegren to be submitted for review based on 1-year data
Narcolepsy - FDA grants tentative approval for manufacturing and marketing of Modafinil
Needle Safety - EPA changes guidelines on disposal of medical needles and syringes
Non-Hodgkin Lymphoma - Non-Hodgkin lymphoma study assesses pesticide levels in carpet dust
Obstetrics - FDA panel backs Accutane registry to prevent drug's use by pregnant women
Occupational Health - CDC publishes new workbook to protect health care workers from sharps injuries
Occupational Health - Focus on disability-adjusted life-years can reduce disease burden
Oral Health - Five billion people worldwide suffer from tooth decay
Osteoporosis - FDA accepts ANDA filing for Calcitonin-Salmon Nasal Spray
Pediatric Obesity - Many kids aware of CDC obesity campaign
Pediatrics - Racial differences in infant death causes in United States reported
Poliomyelitis - Emergency polio immunization campaign hampered by vaccine boycott
Poliomyelitis - Nigeria's neighbors guard against spreading polio outbreak
Prescription Drug Importation - McClellan to lead study of drugs from Canada, over objections
Prostate Cancer - IND application filed to test Modrenal in second indication
Sepsis - NIAID bioterrorism grant to fund a new plasmapheresis device
Sexual and Reproductive Health - E-mail used to alert sex partners of STD exposure
Sexual and Reproductive Health - One of two will have STD by age 25
Smallpox - Smallpox array set developed with CDC completed
Smallpox Vaccine - Physicians decline smallpox vaccination due to inadequate benefits
Smallpox Vaccine - Study shows no vaccinia viremia after smallpox vaccination
Spinal Surgery - Company launches enhanced CD HORIZON spinal system
Surgical Sealant - Biomaterials company completes DuraSeal study enrollment
Systemic Lupus Erythematosus - Riquent NDA accepted for review by FDA
Tobacco Marketing - U.S. government tries to prove tobacco companies lured children
Tremors - FDA gives guidance on special protocol assessment for Altropane study
Tuberculosis Vaccine - M. leprae Hsp65-encoding plasmid DNA induces anti-mycobacterial immunity
Vitamins - FDA approves multivitamin bulk package
West Nile Virus - Infants whose mothers were infected during pregnancy need careful evaluation
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