Schistosomiasis
IL-13 receptor alpha 2 prolongs host survival in schistosomiasis
Published in Medical Letter on the CDC and FDA, March 28th, 2004
"An important feature of many chronic parasitic infections is the ability of the invading pathogen and host to establish a compromise, which ensures successful parasitism without killing the infected host. For many helminth infections, down-modulating the immune response is critical because persistent inflammation can become more damaging to the host than the invading pathogen itself. Such is the case with Schistosomiasis mansoni, where chronic granulomatous inflammation in the liver causes portal hypertension, porto-pulmonary shunting, bleeding from...
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