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Medical Letter on the CDC and FDA

Susan Hasty, Publisher

Table of Contents . . . May 2nd, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications

Clostridium -  Clostridium perfringens characterized using DNA microarray chip

Hepatitis C Vaccine - Envelope protein-based vaccine enhances delays hepatitis C virus infection

Malaria - Co-ligand complex anchors malaria merozoites to erythrocyte invasion receptor

Malaria Vaccine - Sulphadoxine-pyrimethamine pretreatment not recommended for malaria vaccine

SARS - Research response for severe acute respiratory syndrome outlined

Ablation System - Cardiac device firm reports 7.2% decrease in revenues

Acne - FDA approval granted for ANDA for erythromycin/benzoyl peroxide

Alcoholism - Patients with alcohol, drug disorders more likely to have personality disorders

Alcoholism - The demon drink remains largely unaddressed by public health efforts

Anthrax Infection - IND application submitted to FDA for ToxBlox anthrax infection treatment

Bipolar Disorder - New evidence for whole genome linkage in bipolar disorder

Blindness - Leading causes of blindness for blacks and whites different

Colorectal Cancer - Loss of insulin-like growth factor imprinting linked to colon cancer

Complementary & Alternative Medicine - Health food store advice may ignore federal safety advisories on supplements

Dengue Fever - Policymakers' views on dengue fever and need for dengue vaccines outlined

Depression - Elderly get tips to beat back the blues

Diabetes - Pre-IND meeting on diabetic peripheral neuropathy formulation announced

Drug Screening - U.S. patent granted for high throughput drug screening using zebrafish

ECG Monitoring - GMP Cos. announces availability of Lifesync Wireless ECG System

Electronic Medical Records - Company announces U.S. Army contract for Personal Information Carrier

Environment & Health - D.C. agency accused of hiding lead in water

Environmental Pollutants - Organic pollutants detected in giant mussels off the Chilean coast

Environmental Toxins - Comprehensive study: We know little about environment's effects on kids

Epidemiology - Data augmentation helps estimate Legionella subclinical infection rate

Food-Borne Illness - Physicians, nurses and U.S. government release new food-borne illness guide

Gastroenteritis - Waterborne norovirus outbreak in Sweden described

Genital Warts - Positive phase III clinical results achieved with Polyphenon E Ointment

Genomics & Genetics - p21-activated kinase 4 has direct interaction with PDZ-RhoGEF

HIV/AIDS - Cheaper AIDS drugs to be available in U.N.-supported nations

HIV/AIDS - FDA approves OraQuick Rapid HIV Antibody Test for use with oral fluid

HIV/AIDS Opportunistic Infection - Noninvasive assay for P. carinii pneumonia monitoring developed

HIV/AIDS Prevention - CDC grants $21 million to enhance HIV prevention in communities of color

Heart Disease - Enrollment concluded in Taxus V trial; FDA clears Contour SE

Hemostasis - FDA issues 510(k) clearance for D-Stat Dry 3x3 Hemostatic Bandage

Hepatitis - Cell culture and animal models for human viral hepatitis reviewed

Hepatitis C Epidemiology - Prevalence of hepatitis C high among homeless of Oxford, England

Immunology - Acute immune response to filarial parasites characterized by Th1 cytokines

Infectious Disease - Did West Nile virus infection fell Alexander the Great?

Infertility - FDA approves new presentations of Gonal-f to treat infertility

Injury Prevention - Alcohol limit for drunk driving should be much lower

Injury Prevention - Bright clothing and white helmets cut motorcycle deaths

Leishmaniasis -  Leishmania induce Myd88-dependent maturation of splenic dendritic cells

Leishmaniasis Therapy - Treatment of cutaneous leishmaniasis among travelers reviewed

Leukemia - Company completes NDA for clofarabine

Listeria -  Listeria monocytogenes blood agar effective for microorganism isolation

Listeria - Riboprint analysis of applied to Listeria monocytogenes isolates

Lyme Disease - CDC announces new awards for Lyme disease research

Macular Degeneration - NDA submitted for SnET2-PDT to treat wet AMD

Malaria Vaccine - Activity of Plasmodium rhoptry-associated protein peptides reported

Malaria Vaccine - Antibodies to malaria peptide mimics inhibit invasion of erythrocytes

Malaria Vaccine - Erythrocyte-binding antigen of P. falciparum not promising vaccine candidate

Malaria Vaccine - Merozoite surface proteins differ in ability to protect against malaria

Market Analysis - Branded drug-makers prepare for the inevitable

Medicare - Higher spending does not necessarily translate into better care, study finds

Mosquito-Borne Disease - Light-traps are alternative method for sampling adult anophelines

Multiple Myeloma - Phase III pivotal trial for STR begins

Nosocomial Infection - Antimicrobial resistance on the rise in American hospitals

Nutrition - U.S. considers Food Guide Pyramid changes

Obesity - FDA approves LAP-BAND VG System; product hits market

Osteoporosis - Positive phase III data reported for PREOS

Outbreaks - Enterotoxin-producing E. coli O169:H41 outbreaks summarized

Pain - Initial commercialization of Oxycodone 80 mg announced

Pain Therapy - Details reported from FDA meeting on oxymorphone NDAs

Pain Therapy - Results of meeting with FDA on bicifadine reported

Parvovirus B19 - Persistent parvovirus B19 infection without chronic anemia reported

Patents - Kos files suit for infringement of new Niaspan patent

Patient Education - Study reports 90 million Americans have limited health literacy

Pediatric Eye Surgery - FDA grants orphan drug designation for microplasmin in pediatric eye surgery

Pertussis - Assay results for pertussis standardized

Polio Vaccine - Developing country perspective on vaccine-associated paralytic polio released

Prescription Drug Importation - New Hampshire governor unveils state Internet link to Canadian pharmacy

Preventive Medicine - Study: PPOs employ diverse approaches to preventive care for patients

Public Health Policy - Public smoking bans may cut heart attacks

Respiratory Infections - FDA approval granted for Ketek (telithromycin) tablets

Sexually Transmitted Disease - Sexually transmissible infections other than HIV reviewed

Shigellosis Vaccine -  Shigella flexneri 2a vaccine protects against shigellosis symptoms

Skin Cancer - Fresh apple peel extract may have potential chemoprotective effects

Streptococcus - Nursing home patient dies from 'flesh-eating' bacteria

T Cell Lymphoma - HuMax-CD4 gets fast track status

Tremors - Agreement received from FDA on phase III protocol for Altropane

Tuberculosis -  Mycobacterium tuberculosis cultures may represent cross contamination

Tuberculosis Vaccine - BCG vaccination not associated with positive tuberculin test

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