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Monkeypox

Prairie dogs transmit monkeypox to humans

Published in Medical Letter on the CDC and FDA, May 9th, 2004

Prairie dogs transmitted monkeypox to humans in the United States.

"During May and June 2003, the first cluster of human monkeypox cases in the United States was reported. Most patients with this febrile vesicular rash illness presumably acquired the infection from prairie dogs. Monkeypox virus was demonstrated by using polymerase chain reaction in two prairie dogs in which pathologic studies showed necrotizing bronchopneumonia, conjunctivitis, and tongue ulceration," researchers in the United States report.

"Immunohistochemical assays for orthopoxviruses demonstrated abundant viral antigens in surface epithelial cells of lesions in conjunctivae and...

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