Published in Medical Letter on the CDC and FDA, May 9th, 2004
"New tools are urgently needed for the detection of latent tuberculosis (TB). We evaluated the diagnostic potential of two novel Mycobacterium tuberculosis complex-specific candidate antigens (Rv2653 and Rv2654) and investigated T-cell recognition during natural infection in humans and experimental infection in guinea pigs. Peripheral blood mononuclear cells stimulated with peptide pools covering the full length of Rv2654 induced interferon-gamma release in 10 of 19 patients with TB," scientists in Denmark report.
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