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Medical Letter on the CDC and FDA

Susan Hasty, Publisher

Table of Contents . . . May 16th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications

Cancer Therapy - Orlistat is inhibitor of fatty acid synthase with antitumor activity

Drug Resistance - Daptomycin useful for treating drug-resistant Gram-positive pathogens

Parasitology - Common intestinal parasites reviewed

Vaccine Safety - Vaccine Adverse Event Reporting System database reviewed

Wuchereria -  Wuchereria bancrofti infection more prevalent in Haiti lowlands

AIDS/HIV Therapy - Crack cocaine use reduces antiviral therapy use in women with HIV

AIDS/HIV Vaccine - Vaccine allows for infection control in macaques exposed to SHIV

Allergy Medicine - FDA approves Nasacort HFA (triamcinolone acetonide)

Animal Models - Behaviors in three rat strains investigated

Anthrax - Survivors had health problems 1 year after exposure to deadly bacterium

Behavioral Medicine - Husband involvement in child treatment in Guatemala studied

Bioterrorism - Diagnostic algorithm quickly distinguishes anthrax from flu

Biowarfare - Biodefense applications of recombinant polyclonal antibodies reviewed

Breast Cancer - FDA approves computer-aided detection on digital mammography system

Breast Cancer Incidence - Effect of environment on breast cancer risk reviewed

Cardiology - Devices designed to aid in diagnosing and curing arrhythmias

Collaborations - R&D agreement signed with CDC for rapid HIV incidence test

Contraception - FDA approval granted to make Essure at lower-cost site in Mexico

Depression - Blacks less likely to show suicide factors

Diagnostics - Room illuminance affects monitor calibration

Diagnostics - Ultrasound assessments of bone status can help where DXA is inaccessible

Drug Safety - Health experts warn about growing danger of counterfeit drugs

Echocardiography - Portable echocardiograph no substitute for standard echocardiography

Enterococcus - FMN-dependent azoreductase from Enterococcus faecalis characterized

Fetal Alcohol Disorders - Experts agree to focus on range of disorders stemming from maternal drinking

Fetal Medicine - Difluoromethylornithine has few effects on body weight in rats

Fetal Medicine - Transplacental exposure to 5-AZA-CdR affects behavior of male mice

Finance - Major healthcare-products company's first quarter sales increase 17.7%

Food-Borne Illness - Near-real-time method to monitor bacteria in Atlantic aquifer described

Generic Drugs - Tentative approval for risperidone tablets; potential first-to-file opportunity

HIV Therapy - FDA grants clearance for HIV viral entry inhibitor to begin phase Ib/IIa trial

HIV/AIDS - Effect of HIV infection on NK cell inhibitory receptors clarified

HIV/AIDS - FDA grants traditional approval status to Ziagen

HIV/AIDS Risk - HIV-positive teens not aware of risks and delay treatment

HIV/AIDS Trends - There is hope among grim facts with AIDS

Health Risk - Agency says premature heart-related deaths more likely in Appalachia

Healthcare Interventions - StepWatch receives FDA clearance

Heart Disease - Report shows heart disease huge but underappreciated global problem

Hypercholesterolemia - Trans fat linked to increase in cholesterol

Immunology - ImmuneRegen BioSciences to form bioterrorism advisory board

Immunology - Interleukin-2 plays key role in Th2 polarization

Influenza - APIC initiative to address low flu-shot rate among healthcare workers

Influenza - Flu shot makers say orders filling up fast for next season

Influenza - Many health care workers not getting flu shot

Leishmaniasis - Vaccine containing Leishmania and BCG effective for leishmaniasis

Malaria Vaccine -  P. vivax merozoite surface protein shows promise as malaria vaccine

Malaria Vaccine - Disulfide bonds in malaria surface protein impede antigen processing

Malignant Melanoma - National Cancer Institute grant to fund phase II study of INGN 241

Measles Vaccine - Misdiagnosis of measles negatively impacts health workers' confidence

Melanoma Vaccine - IL-2 improves metastatic malignant melanoma response to vaccine

Mother-To-Child HIV Infection - UNICEF says project in Rwanda registers high acceptance rate

Mycology - RING-finger-like protein Ini1 essential for cell cycling in yeast

Nicotine Addiction - Study: Smoking risk rises for teens after end of antitobacco campaign

Nipah Virus - Nipah virus conforms to rule of six in minigenome replication assay

Parkinson Disease - FDA approves Apokyn for the acute treatment of episodes of immobility

Patents - Company announces issuance of second Cardiosonix patent

Pediatrics - Study: Up to 75% of U.S. children, adolescents don't get appropriate care

Prescription Drug Importation - Maryland county, home to FDA, to recommend buying drugs from Canada

Prion Disease - Quinacrine is candidate for the treatment of prion diseases

Prion Disease - Variations in infectious protein determine prion strain differences

Public Health - European public health at risk as EU border extends to the east

Research and Development - Successful completion of milestone triggers Protexia drug development

Rotavirus Vaccine - Rotavirus typing methods and algorithms reviewed

Sexual & Reproductive Health - Trichomoniasis found pervasive among high-risk populations

Skin Cancer - Aldara deemed approvable by U.S. FDA

Stents - First patient enrolled in carotid-stent clinical trial

Stomach Acid - FDA approves reformulation of Protonix IV for Injection

Tobacco Use - Study shows tobacco use on decline among Ohio teens

Vaccine Development - Polysaccharide vaccine induces polysaccharide-reactive T cells in mice

Violence - Rwanda: Aid plea for genocide rape survivors

Weight Loss - Obesity patients not getting advice

Women's Health - African ambassadors seeking international help for women's health in Africa

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