Medical Letter on the CDC and FDA

Hepatitis C Epidemiology - Risk factors for hepatitis C in Alaska natives reported

Hepatology - Chronic liver disease mortality in the United States reported

Malaria Transmission - Isonicotinic acid hydrazide inhibits malaria transmission in mosquito

Malaria Vaccine -  Plasmodium falciparum peptides bind to human hepatocytes

Pancreatic Cancer - No link found between IGF or IGF-binding protein and pancreatic cancer

AIDS Therapy - FDA-approved study launched to treat AIDS patients in virologic failure

AIDS/HIV Genomics and Genetics - Wild-type CCR5 confers HIV-1 cross-clade resistance

AIDS/HIV Vaccine - Components of HIV vaccine are recognized by T-helper cells

AIDS/HIV Vaccine - IL-15 may be beneficial for AIDS immunotherapy

Adverse Drug Effects - Long-term studies show transduced stem cells do not cause leukemia

Age-Related Macular Degeneration - Phase III squalamine trials slated for early 2005

Angiology - Trial starts for device designed to trap clot-causing debris during angioplasty

Anthrax Vaccine - Membranal polypeptides of Bacillus anthracis identified

Assisted Reproduction - CDC releases ART Surveillance report for 2001

Business & Finance - Software company receives additional funding for cancer diagnostics research

Cancer Risk Factor - Unique gene sets distinguish cirrhosis patients with a risk for liver cancer

Cancer Therapy - Companies announce Genasense EAP for those with advanced melanoma

Childhood Immunization - Millions of under-immunized children at risk from cross-border infections

Chronic Liver Disease - Pioglitazone shows promise for treating non-alcoholic steatohepatitis

Clinical Update - Neoprobe provides clinical update following meeting with FDA

Complementary & Alternative Medicine - Levels of aristolochic acids in Chinese herbs determined by NMR

Depression - FDA grants approval for generic form of Remeron

Diabetes Pathogenesis - PPAR-alpha deficiency does not alter insulin sensitivity in mice

Diabetes Prevention - Government diabetes campaign targets high-risk groups

Diagnostics - Real-time PCR kit detects E. coli O157 in bovine fecal samples

Diet and Nutrition - Reference materials program for dietary supplements outlined

Disease Outbreak - CDC team to investigate Mobile County TB cases

Drug Development - Company updates timing for GlycoPEG-EPO IND filing

Emerging Diseases - Center established to study new virus and terror

Endocrinology - FDA requires pancreatic extract manufacturers to submit marketing applications

Finance - Biopharmaceutical company reports strong first-quarter sales

Food-Borne Illness - Arsenic determined in infant food products by IC-ICP-MS

Generic Drugs - Company receives tentative approval for Ofloxacin Ophthalmic Solution

HIV/AIDS Therapy - HIV patients get long-term boost with short, intermittent drug regimen

Hepatitis C - Substance abuse experts call for government backing to prevent hepatitis C

Hepatitis Vaccine - Hepatitis A/B vaccine cost-effective substitute for hepatitis B vaccine

Herpesvirus - Human herpesvirus-8 oral shedding higher without antiretroviral therapy

Hyperglycemia - FDA approval granted for rapid-acting insulin analogue Apidra