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Age-Related Macular Degeneration

Phase III squalamine trials slated for early 2005

Published in Medical Letter on the CDC and FDA, May 23rd, 2004

Genaera Corp. (GENR) announced that the U.S. Food and Drug Administration (FDA) has cleared Genaera's investigational new drug (IND) application for its systemically administered antiangiogenic drug, squalamine.

The IND covers treatment of neovascular diseases of the eye, including subfoveal choroidal neovascularization associated with age-related macular degeneration, known as "wet" AMD. Genaera also announced they plan to begin phase II trials in AMD this quarter, and these phase II trials will run concurrently with the start of phase III trials in AMD, beginning in early 2005.

"One of Genaera's highest priorities is expediting squalamine's...

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