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AIDS Therapy

FDA-approved study launched to treat AIDS patients in virologic failure

Published in Medical Letter on the CDC and FDA, May 23rd, 2004

Advanced Biotherapy, Inc., (ADVB) announced the launch of a phase I U.S. Food & Drug Administration (FDA)-approved clinical trial to initially treat antiretroviral drug-resistant AIDS patients with an inhibitor to Tumor Necrosis Factor-alpha (TNF-alpha).

The trial is being conducted by researchers at Georgetown University.

The study's enrollment at the outset is limited to 10 patients who are in virologic failure and no longer able to benefit from the administration of Highly Active Anti-Retroviral Therapy (HAART). It is estimated that more than 50% of AIDS patients ultimately become non-responsive to such drugs during the course of their...

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