Mycobacterium
M. tuberculosis strain with resistance to isoniazid identified
Published in Medical Letter on the CDC and FDA, May 30th, 2004
"We have identified a potential quality control strain of Mycobacterium tuberculosis to monitor isoniazid susceptibility testing. This strain (strain A) has a stable phenotypic low-level resistance to isoniazid, has a mutation of C (-15) --> T in the inhA promoter region, and gave consistent susceptibility test results in 141 laboratories," wrote Bereneice M. Madison at the Centers for Disease Control Prevention and collaborators in the United States.
Madison and associates published their study in the Journal of Clinical...
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