Susan Hasty, Publisher
Table of Contents . . . June 6th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications
Charcot-Marie-Tooth Disease - Ascorbic acid corrects phenotype of Charcot-Marie-Tooth disease
Hepatitis - Molecular epidemiology of hepatitis B and C infections in Asia reviewed
Hepatology - Chronic liver disease mortality in the United States reported
Influenza - Pandemic influenza can be contained with antiviral agents
Malaria Transmission - Isonicotinic acid hydrazide inhibits malaria transmission in mosquito
AIDS/HIV Genomics and Genetics - Wild-type CCR5 confers HIV-1 cross-clade resistance
AIDS/HIV Transmission - Maternal malaria and perinatal HIV transmission interaction complicated
AIDS/HIV Vaccine - Components of HIV vaccine are recognized by T-helper cells
AIDS/HIV Vaccine - IL-15 may be beneficial for AIDS immunotherapy
AIDS/HIV Vaccine - Virus-like particles rich in HIV-1 envelope gp120 developed
Allergy Medicine - Mice exposed to formaldehyde exhibit different inflammatory responses
Animal Models - Animal studies used to determine risks of environmental toxicants
Animal Research - Northwestern records on animal research inquiry subpoenaed by U.S. government
Anthrax Vaccine - Membranal polypeptides of Bacillus anthracis identified
Antibiotics - Novel inhibitors of bacterial RNA polymerase I characterized
Ataxia-Telangiectasia - Antioxidant corrects neurobehavioral defect in ataxia-telangiectasia
Avian Influenza - Avian influenza may be new pandemic threat
Benign Prostatic Hyperplasia - New FDA-approved catheter designed to treat shorter prostate lengths in BPH
Bubonic Plague - Flea-borne transmission model evaluates vaccines against bubonic plague
Business Update - Company submits IND to the FDA for ALS; announces the resignation of CEO
Cervical Cancer - WHO agency confirms efficacy of screening women 25-65 to reduce mortality
Chlamydia - Incidence of chlamydial infection at all-time high in Washington state
Chlamydia - Prevalence of chlamydial infection high among young adults in U.S.
Colon Cancer - Company launches colon cancer trial with GTI-2040
Complementary and Alternative Medicine - Levels of aristolochic acids in Chinese herbs determined by NMR
DNA Research - 4-methylthio-1-butyl group protects phosphate/thiophosphate groups
Diabetes Pathogenesis - PPAR-alpha deficiency does not alter insulin sensitivity in mice
Diet and Nutrition - Reference materials program for dietary supplements outlined
Drug Delivery - FDA approves Vitrase for use as a spreading agent
Emergency Contraception - Ob/gyn group issues statement on FDA's non-approval of OTC status for Plan B
Environmental Health - CYP1A2 is not required for dioxin-induced immunosuppression
Environmental Health - Developmental pharmacology principles applied to environmental toxins
Environmental Health - Mercury exposure and child development outcomes reviewed
Environmental Health - Vaccine-derived poliovirus isolated from stream waters in Hispaniola
Finance - Affinitak maker reports decrease in revenues during first quarter
Finance - CardioSEAL maker announces increased first quarter revenue
Food-Borne Illness - Arsenic determined in infant food products by IC-ICP-MS
Food-Borne Illness - Gene probes for quantifying Vibrio in crabmeat evaluated
Generic Drugs - Company receives first-to-file status on gabapentin tablets
HIV/AIDS Prevention - Experts say hunger and AIDS create vicious cycle in Africa
Healthcare Access - WHO: More AIDS clinics needed in countries
Healthcare Costs - HMS teams with MDwise to coordinate benefits for Medicaid managed care
Heart Disease Risk Factor - Role of noninvasive studies in risk for sudden cardiac death reviewed
Hemorrhagic Fever - Crimean-Congo hemorrhagic fever virus genome L RNA segment sequenced
Hepatitis - Site provides information about hepatitis infection and therapy
Hepatitis C Epidemiology - Risk factors for hepatitis C in Alaska natives reported
Hepatitis C Therapy - Immune responses in patients with hepatitis C and HIV described
Hepatitis Vaccine - Hepatitis A/B vaccine cost-effective substitute for hepatitis B vaccine
Hepatitis Vaccine - Hepatitis vaccination in patients with chronic liver disease reviewed
Herpesvirus - Human herpesvirus-8 oral shedding higher without antiretroviral therapy
Hypertension - NDA submitted for nebivolol
Immunotherapy - CpG oligodeoxynucleotides find immunotherapeutic use
Legal Issues - Annan to contact Libyan government over death sentences for six health workers
Legal Issues - Libyan protesters burn American flag to denounce U.S. criticism of AIDS trial
Leishmaniasis - Cross-talk between CD8+ and CD4+ T cells occurs in leishmaniasis
Leishmaniasis - Leishmaniasis in Brazil is a disease of urban-rural interface
Liver Cancer Risk Factor - Most hepatocellular carcinoma in West Africa caused by hepatitis B
Malaria - Circumsporozoite antigens quantified in Plasmodium-infected mosquitoes
Malaria - Malaria sporozoites infect cells by two pathways
Malaria - Rare mutation in gene of P. falciparum isolates identified
Malaria Genomics and Genetics - Genotypes of malaria-infected patients in Papua New Guinea reported
Malaria Vaccine - Plasmodium falciparum peptides bind to human hepatocytes
Malaria Vaccine - Plasmodium gametocyte stages neglected in vaccine development
Malaria Vaccine - Displacement in 6725 SERA peptide analogue protects against malaria
Malaria Vaccine - Malaria vaccine results indicate protection related to antibody levels
Malaria Vaccine - Response to conserved epitope linked to protection from malaria
Malaria Vaccine - Vaccine genes of P. falciparum during hepatic phase identified
Malaria Vaccine - X-ray analysis conducted on protein vaccine candidate for malaria
Measles Vaccine - Aerosol better than subcutaneous delivery for measles booster
Metapneumovirus - Human metapneumovirus infection similar in severity to RSV in children
Ophthalmology - Presence of certain eye disorders linked with poorer survival rates
Pain Therapy - Animal studies show promise treating severe chronic pain
Pancreatic Cancer - No link found between IGF or IGF-binding protein and pancreatic cancer
Pneumococcal Disease - Predictors of pneumococcal carriage and resistance in children reported
Pneumococcal Disease - Vaccine reduces racial disparity in incidence of childhood pneumonia, meningitis
Pneumococcal Vaccine - Two pneumococcal vaccines safe and effective in American Indian infants
Political Conflict - Women suffering brunt of conflict in Western Sudan, UNFPA warns
Proteomics - Model to assess risk of non-ionizing pulsed radiation developed
Proteomics - Protein folding 'speed limit' estimated
Public Health - Cost analysis of bike and pedestrian trails outlined
Public Health - Methods for ranking cities by public health criteria reported
River Blindness - Studies show success of Mectizan partnerships
Rubella Epidemiology - Rubella in developing countries still causing blindness and deafness
SARS Vaccine - DNA vaccine induces SARS coronavirus protective immunity in mice
SARS Vaccine - Passive transfer of antibody prevents SARS replication
Sexual And Reproductive Health - FDA issues not approvable letter for OTC "morning after" pill
Smallpox - Imvamune smallpox vaccine clinical study to include eczema patients
Smallpox - Third-generation vaccine against smallpox tested
Smallpox Vaccine - Method developed to monitor immune response against vaccinia virus
Smallpox Vaccine - Prevalence of dermatologic reactions to smallpox vaccine reported
Solid Cancer - Advances in molecular carcinogenesis reviewed
Sudden Cardiac Death - Researcher finds genetic explanations for some previously unexplained deaths
Technology - New modeling grants target epidemics, bioterror
Toxicology - Fate of chemicals in skin after dermal application investigated
Tumor Suppressor Gene - Large intestinal tumors induced by o-Nitrotoluene in B6C3F1 mouse model
Typhoid Fever - Method to diagnose typhoid fever using antigens in urine developed
Vaccine Safety - MMR vaccine controversy offers insights into health risk communication
Vectors and Zoonoses - Simple assay developed to assess feeding habits of Meprai spinolai
Violence - Higher rates of trauma increase urban American Indian women's risk for HIV
Yellow Fever Virus - Wild-type yellow fever virus linked to 17DD vaccine characterized
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