Smallpox Vaccine

Prevalence of dermatologic reactions to smallpox vaccine reported

Published in Medical Letter on the CDC and FDA, June 6th, 2004

Researchers report the prevalence of benign dermatologic reactions to smallpox vaccination in adults in a recent issue of Clinical Infectious Diseases.

"A phase 1 smallpox vaccine trial involving 350 adult volunteers was conducted. Of these subjects, 250 were naive to vaccinia virus vaccine (i.e., 'vaccinia naive'). Volunteers received a new cell-cultured smallpox vaccine or a live vaccinia virus vaccine," scientists in the United States report.

"Nine self-limiting rashes (3.6%) were observed in the vaccinia-naive group," said Richard N. Greenberg and collaborators at the University of Kentucky and DynPort Vaccine Company. "None of the...

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Source: Medical Letter on the CDC and FDA (2004-06-06)

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