Susan Hasty, Publisher
Table of Contents . . . July 4th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications
Bartonella - Diversity of Bartonella in rodents of Thailand determined
Cancer Screening - U.S. National Cancer Institute in vitro drug screening has expanded
Colon Cancer - States awarded grant for colorectal cancer prevention educational program
MMR Vaccine - Measles-mumps-rubella vaccination recommended at 12 to 15 months of age
Outbreaks - Model for disease outbreaks in realistic urban networks developed
Age-Related Macular Degeneration - SnET2 NDA accepted by FDA with priority review designation
Allergy Medicine - National study shows 82% of U.S. homes have mouse allergens
Amyotrophic Lateral Sclerosis - Link suspected between soccer and amyotrophic lateral sclerosis
Anemia - Special protocol assessment agreed on for approval-enabling study of Ranexa
Anthrax - CDC collaboration yields new test for anthrax
Anthrax - NIH supports phase I clinical trial of DNA-based anthrax vaccine
Anthrax - Public-private partnership extends Dutch-American cooperation in biodefense
Anthrax Vaccine - B. anthracis antigens for testing anthrax immunity identified
Anti-Infectives - Antimicrobial drug development declining
Atrial Fibrillation - FDA issues non-approvable letter for Revelation Tx
Benign Prostatic Hyperplasia - Biotech firm submits response to FDA warning letter
Bioterrorism - Defense Department starts first responder tech center at Pitt
Biowarfare - Vaccines for the prevention of diseases caused by potential bioweapons
Blood Glucose Monitoring - TrueTrack Smart System receives FDA approval for alternate site testing
Breast Cancer - Application filed for European marketing approval of RSR13 (efaproxiral)
Breastfeeding - FDA warns against women using domperidone to increase milk production
Cancer Epidemiology - Annual report finds cancer incidence and death rates on the decline
Cancer Risk - Illinois holding international conference on PCBs
Cancer Therapy - Companies end Genasense expanded-access program in melanoma
Cancer Therapy - Near-infrared labeled endostatin localizes at tumors in animal models
Cardiac Arrest - FDA issues marketing clearance for AED Plus pediatric capability
Cardiovascular Stents - U.S. patent issued relating to biocompatible HAp coating technology
Clinical Studies - Company initiates Diquafosol phase III dry eye trial
Clinical Studies - Panel recommends CHARITE artificial disc for FDA approval
Contraception - Pregnancy more likely from one act of unprotected sex than previously believed
Cord Blood Stem Cells - U.S. Patent Office requested to re-examine cord blood stem cell patent
Coronary Angioplasty - FDA does not approve application to amend existing Angiomax label
Dengue Fever - IgG1 antibody for neutralization of dengue type 4 virus identified
Diagnostics - FDA approves Second Look 200 for breast-cancer detection
Diagnostics - FDA approves expanded labeling claims for SurePath Liquid-Based Pap Test
Diagnostics - Zargis Acoustic Cardioscan cleared for marketing
Disease Prevention - Connecticut receives $3 million for Lyme disease study
Drug Development - Recombinant anti-MUC1 scFv has improved stability
Endografts - FDA approves Zenith FLEX AAA endograft
Environmental Health - MS method to measure toxaphene congeners in human serum developed
Environmental Toxins - Lead levels not as safe as previously thought
Epidermolysis Bullosa - Thymosin Beta 4 receives Orphan Drug designation for Epidermolysis Bullosa
Erosive Esophagitis - Prevacid IV for Injection approved by the FDA for erosive esophagitis
Food-Borne Illness - E. coli O157:H7 outbreak linked to salami in British Columbia
Food-Borne Illness - Bioassay suitable for screening of enrofloxacin residues in chicken
Food-Borne Illness - LC/MS analysis of brevetoxin metabolites in Eastern oyster reported
Gastroenterology Vaccine - Progress in enteric vaccine development outlined
Genetic Disorder - Aminoglycoside rescues disease-causing mutation in vasopressin receptor gene
Genomics - FDA, NIH drive clinical genomics: Is widespread application in the near future?
Global Health - Referral to district hospitals key to improving care for severely ill children
HIV/AIDS Prevention - Experts say AIDS prevention and treatment should be integrated to fight epidemic
HIV/AIDS Treatment - Drugs donated by AIDS patients in U.S.helps prolong lives worldwide
HIV/AIDS Treatment - G-8 adopts plan to speed HIV vaccine development
HIV/AIDS Trends - Cases of HIV-infected newborns decline in New York
Health - FDA certificate to export products to Japan granted for RespAide
Hemorrhagic Fever - West Nile virus trial expands to include additional lethal viruses
Hepatitis B Virus - Low-level viremia of hepatitis B found in antibody-positive blood donor
Hereditary Angioedema - FDA permission granted to resume DX-88 clinical trials
Hypercholesterolemia - U.S. FDA grants tentative approval to market fenofibrate tablets
Immunology - Interferon-gamma attenuates interferon-alpha activity in liver cells via STAT1
Immunology - Interleukin-6 obstructs T cell-mediated hepatitis
Injury Prevention - CDC study shows impact of water dangers
Injury Prevention - Frequency of violent behavior among youths similar in different countries
Legal Issues - Federal appeals court says Arizona twins should get Social Security benefits
Legal Issues - United States senators target dietary supplement law
Leukemia - FDA begins priority review of NDA for clofarabine in pediatric acute leukemia
Liver Metastases - Hepatic artery infusion has high partial response but no longevity benefit
MMR Vaccine - Economic analysis of two-dose MMR vaccination program in U.S. reported
Malaria Research - UCSD partners with Peru in NIH grant to battle world's number 2 killer
Measles - CDC lifts suspension of adoptions from Chinese agency
Measles Epidemiology - Epidemiology of measles in the United States from 1997-2001 reported
Measles Epidemiology - Measles outbreak epidemiology in the U.S. in 1993-2001 reported
Measles Epidemiology - Minimum investigation rate for evaluating measles monitoring proposed
Measles Epidemiology - Surveillance is adequate to detect endemic measles in the U.S.
Measles Survival and Mortality - Acute measles mortality in the United States during 1987-2002 reported
Measles Survival and Mortality - Measles hospitalizations during 1985-2002 in U.S. reported
Measles Vaccine - Disparity in measles vaccine coverage in minority children eliminated
Measles Vaccine - Vaccination levels associated with lack of measles in preschoolers
Measles Vaccine - Vaccine-induced antibodies to measles persist 26 to 33 years
Measles Virus - Genetic analysis of measles viruses in U.S. performed
Measles Virus - Measles elimination goals assessed
Measles Virus - Measles elimination in U.S. aids global measles elimination efforts
Measles Virus - Measles virus shedding does not occur with inapparent measles infections
Measles Virus - Overview of measles surveillance in the United States released
Medical Device - Noise in flat-panel displays with subpixel structure investigated
Medical Ethics - Ethics of vaccine research reviewed
Meningitis - Unique variant of disease-causing meningococci characterized
Migraine - FDA issues not-approvable letter for MT 100 migraine treatment
Multiple Sclerosis - Application submitted to European Medicines Agency for Antegren approval
Myelodysplastic Syndromes - First component of Dacogen New Drug Application submitted to FDA
Nutrition - Exercise, fish oil supplements great for the heart
Oncology - New models offer insight into the mechanics of thalidomide analogues
Osteoporosis - PAI complete for nasal-spray facility
Overactive Bladder - Company announces FDA approval of SANCTURA
Overactive Bladder - U.S. FDA approves Sanctura for treatment of overactive bladder
Pharmaceutical Drugs - FDA accuses maker of antiretroviral of misleading promotions
Pneumococcal Vaccine - Pneumococcal vaccine not cost-effective for all elderly adults
Pneumococcal Vaccine - Pneumococcal vaccine prevents pneumococcal disease but not pneumonia
Polio Vaccine - Vaccine-derived poliovirus isolated from sewage in Estonia
Postoperative Ileus - Second portion of NDA submitted for Entereg
Prion Disease - Scrapie protein degraded by cysteine proteases in dendritic cells
Prostate Cancer - Positive phase IIb data reported for ACAPODENE
Public Health - Fluoroscopic safety program at large research hospital described
Public Health - Smoking, obesity connected to income levels and education, analysis shows
Regulatory Issues - Dietary supplement law said inadequate
Regulatory Issues - FDA rejects Illinois drug import pilot program
Rotavirus - Simple method for storage of rotavirus RNA in stool samples developed
SARS Vaccine - DNA vaccines target nucleocapsid protein of SARS coronavirus
Salmonella - Salmonella enterica Javiana infections linked to amphibian contact
Sexually Transmitted Disease - Guide to sexually transmitted disease resources on Internet released
Smallpox - Smallpox as biological weapon reviewed
Thrombosis - New Arixtra indications: Acute deep venous thrombosis, acute pulmonary embolism
Transduction - Electric field-induced molecular vibration forges DNA transfer
Tuberculosis Vaccine - Pantothenate auxotroph of M. tuberculosis protects guinea pigs
Uterine Fibroids - FDA panel recommends ExAblate System for approval
Virology - Proteasome inhibition boosts viral replication in an HBX-dependent manner
Water-Borne Illness - Filtration protects patients from pathogens in hospital water
West Nile Virus - Company receives approval for WNV protocol with Alferon N treatment
West Nile Virus - SYBR green-based assay detects 100% of West Nile virus target region variants
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