Diagnostics

Method developed to quantify tetracyclines in food using LC

Published in Medical Letter on the CDC and FDA, July 11th, 2004

Scientists have developed a method to quantify tetracyclines in food using liquid chromatography (LC) with electrochemical detection.

"Mixed-valent films of ruthenium oxide-ruthenium cyanide were electrodeposited onto glassy carbon and characterized for the electrocatalytic oxidation of tetracycline. The currents produced by tetracycline were higher than from previously reported electrode modifications or pretreatments. In H₂ SO₄ pH 1.0 + 0.5M K₂ SO₄ , the second-order rate constant for the reaction between tetracycline and the Ru(III/IV) couple of ruthenium oxide was 3x10⁵±1x10⁵...

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Source: Medical Letter on the CDC and FDA (2004-07-11)

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