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Listeria

CpG oligodeoxynucleotides improve survival after Listeria infection

Published in Medical Letter on the CDC and FDA, August 15th, 2004

CpG oligodeoxynucleotides improve the survival of pregnant and fetal mice following Listeria monocytogenes infection.

According to a study from the United States, "Listeria infection during pregnancy can cause the death of both mother and fetus. Previous studies established that immunostimulatory CpG oligodeoxynucleotides (ODN) increase the resistance of healthy adult mice to many infectious pathogens, including Listeria monocytogenes. This study examines whether the innate immune response elicited by CpG ODN can reduce the susceptibility of pregnant mice to lethal Listeria challenge."

"The results indicate that CpG ODN...

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