Influenza Vaccine
RNA interference protects against lethal influenza virus challenge
Published in Medical Letter on the CDC and FDA, August 22nd, 2004
According to published research from the United States, "Influenza virus infection is responsible for hundreds of thousands of deaths annually. Current vaccination strategies and antiviral drugs provide limited protection; therefore, new strategies are needed. RNA interference is an effective means of suppressing virus replication in vitro. Here we demonstrate that treatment with small interfering RNAs (siRNAs) specific for highly conserved regions of the nucleoprotein or acidic polymerase inhibits influenza A virus replication in vivo."
"Delivery of these siRNAs...
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