Published in Medical Letter on the CDC and FDA, August 22nd, 2004
"We analyzed endothelial cell membrane microparticles (ECMP) in the peripheral blood of patients with paroxysmal nocturnal hemoglobinuria (PNH) (n=9), aplastic anemia (AA) (n=10), sickle cell disease (SCD) (n=8), and healthy donors (HD) (n=11). There was no clinically manifested thrombosis in the PNH or AA group, except one cured thrombophlebitis (PNH), while all SCD patients had a history of vaso-occlusive crises. We used three-color flow cytometry with blood cell-specific antibodies and antibodies to endothelial antigens CD105 and CD144. Phosphatidylserine-positive...
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