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AIDS/HIV Diagnosis

IgG-capture BED-enzyme immunoassay detects recent HIV seroconversion

Published in Medical Letter on the CDC and FDA, August 29th, 2004

The immunoglobulin G-capture BED-enzyme immunoassay is an effective method to detect recent human immunodeficiency virus type 1 seroconversion.

According to a study from the United States, "Recently, we developed an immunoglobulin G (IgG)-capture BED-enzyme immunoassay (BED-CEIA) to identify recent human immunodeficiency virus (HIV) type 1 (HIV-1) seroconversion for use in incidence estimates. We have established an algorithm for its use; developed quality control reagents to monitor the assay; and evaluated its performance for interrun, intrarun, and operator variability."

"Analysis of 144 individual plates, which involved multiple plate lots and...

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