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Susan Hasty, Publisher Table of Contents . . . September 5th, 2004 Non-Subscriber - Summaries Only Related Areas: Other Issues in Medical Letter on the CDC & FDA | Other Publications
Alcoholism - Mass media campaigns effective for reducing alcohol-involved crashesDiabetes Survival & Mortality - Diabetes increases cancer mortality risk for some cancer typesFood-Borne Illness - Antimicrobial drug delivery in food animals reviewedHIV/AIDS Epidemiology - American Indians and Alaska natives surveilled for HIV/AIDS and risk behaviorsMalaria - Retrospective of re-infection of humans with Plasmodium publishedAIDS/HIV Pathogenesis - Malnutrition increases risk of acquired immunodeficiency syndromeAIDS/HIV Vaccine - DNA prime-MVA boost HIV vaccine tailored for eastern and central AfricaAddiction Medicine - Buprenorphine for treatment of opiate dependence reviewedAddiction Medicine - FDA approves Campral Delayed-Release Tablets for treating alcohol dependenceAllergy Medicine - Quaternary ammonium compounds exhibit adjuvant effect in murine modelAlzheimer Disease - Transgenic animal models of Alzheimer disease reviewedAngina - Trial of Ranexa initiated for certain patients with chronic anginaAngiology - Inflammatory cytokines referee angiogenic control during inflammationAntioxidants - Induction of metallothionein requires transcription factor and zincAvian Influenza - Scientists warn about pandemic potential of lesser-known bird flu strainBioterrorism - Nebraska proposes 10-state bioterrorism allianceBlood Donations - Company introduces enhanced red cell collection technologyBotulinum Toxin - Novel method developed to quantify botulinum neurotoxin antibodiesBreast Cancer - Orphan drug designation granted from U.S. FDA for EfaproxynBreast Implants - 7-year deflation rate data filed for breast implants post approval survey studyBreastfeeding - Public beliefs about breastfeeding policies in various settingsBusiness & Finance - Company reports $8.8M Q2 loss, provides clinical updateBusiness Update - Generics producer granted rights for fluconazole, intends to file antiretroviralCancer Therapy - Antibody-targeted radiation cancer therapy reviewedCancer Vaccine - Mesothelin is new target for immunotherapy of mesotheliomasCancer Vaccine - Viral chemokine fusions trigger antitumor immunity independent of chemotaxisCardiovascular Disease - FDA approves Lipitor to lower risk of heart attacksCardiovascular Disease - Pre-IND meeting held with FDA for platelet aggregation inhibitorChickenpox - Varicella vaccine reduces contagiousness of chickenpoxCholera Vaccine - V. cholerae polysaccharide fragments are immunogenic in miceColon Cancer - Clinic's participation in colon cancer drug study provides access to new therapyDepression - FDA approves Cymbalta for the treatment of depressionDepression - Physician notification program launched for kids on antidepressantsDiabetes Epidemiology - Millions of American Indians, Alaska Natives at risk for type 2 diabetesDiagnostics - Company launches FDA-cleared high sensitivity Troponin I assayDiagnostics - FDA provides clearance for MAGNETOM C!Diagnostics - Monocyte activation test for parenteral drug contaminants developedDiagnostics - U.S. FDA clearance given for herpes simplex virus assayDiet and Nutrition - Mothers misunderstand questions on feeding questionnaireDrug Development - Biopharmaceutical company initiates clinical trial of TRX4 for psoriasisDrug Development - Orphan drug designation granted for key component in liver assist programDrug Development - U.S. FDA approves new drug application for generic topical cortisone ointmentDrug Development - U.S. FDA grants orphan drug designation for pulmonary arterial hypertension drugDrug Security - Drug companies approach brand security issue head on, study showsEbola - WHO announces end of Ebola outbreak in southern SudanEndocrine Disorders - Methylprednisolone Sodium Succinate approved by FDAEnvironmental Health - EPA orders end to 'wet method' asbestos removal at airport projectEnvironmental Toxins - Disagreements over fluoridation of public water still strong after 50 yearsEnvironmental Toxins - Tobacco industry attempted to influence reporting on secondhand smokeFetal Alcohol Syndrome - New hope for children with fetal alcohol syndromeFinance - Oncology-focused biopharma reports record product revenues Q2 2004Finance - Pharmaceutical company reports second quarter resultsFunding - Tuberculosis prevalence rates in China fall after DOTS introduced by WHOGenetic Abnormalities - Ariol 2.0 launched as next-generation cellular imaging systemGenomics - Scientists announce breakthrough in pathway engineeringGeriatrics - Study examines inappropriate medication prescribing for elderly patientsGlaucoma - Approvable letter issued by FDA for LumiganHIV/AIDS Coinfection - HSV-2 infection increases risk of HIV transmissionHIV/AIDS Epidemiology - Condom use reduces rate of new HIV infections in ThailandHIV/AIDS Prevention - HIV prevention drug gets U.S. FDA clearance to advance in phase 1 clinical trialHIV/AIDS Research - Noninfectious X4 but not R5 HIV-1 inhibits lymphoid tissue antibody responseHIV/AIDS Treatment - Comprehensive strategy needed to access antiretroviral treatment in South AfricaHIV/AIDS Treatment - FDA approves Sculptra (injectable poly-L-lactic acid)HIV/AIDS Treatment - FDA approves two fixed-dose combination drug products for HIV-1 infectionHIV/AIDS Treatment - U.S. FDA approves Truvada as part of HIV combination therapyHIV/AIDS Treatment - US$5-6 billion needed by 2005 to provide ART to low-, middle-income countriesHealthcare Coverage - GLIADEL Wafer assigned new DRG designation
Healthcare Funding - Japan gives Cambodia nearly US$25 million for healthcareHepatitis Epidemiology - Seroprevalence of markers of viral hepatitis in Yemeni healthcare workersHypogonadism - Trial finds effective treatment for testosterone replacementIllicit Drugs - Feds say "club drug"-related visits to ERs show some sharp declinesImmunology - VIG product submitted for FDA approvalImmunotherapy - Human B cells are alternative source of efficient antigen-presenting cellsInfection Control - Day of week and collection length vital to nosocomial infection surveysInfectious Disease - Rodent prey reduce reservoirs of transmissible pathogensInfluenza - CDC: Flu shot effective more than half of the timeInfluenza - Company delivers first million doses of Fluvirin vaccine to U.S. distributorsInfluenza - First influenza vaccine shipped to healthcare providersInfluenza - Influenza causes excess hospital admissions in Hong KongInjury Prevention - CDC: Animals cause more than 26,000 roadway injuries each yearLeishmaniasis - Action in Afghanistan aims to control debilitating diseaseLeukemia - Cell loading system used in phase I/II gene therapy trial for leukemiaLyme Disease Vaccine - Lyme borreliosis from infection to autoimmunity reviewedMalaria - Fever temperature linked to malaria infectivity rateMarket Analysis - Forecasting company predicts anticholesterol market share for VytorinMeasles - CDC: Measles cases lowest since 1912Medical Devices - Company begins human clinical trial in age related macular degenerationMedical Devices - Heart device maker comments on CMS VAD reimbursement notice in Federal RegisterMedical Devices - New laser eye surgery policies established by U.S. veteran's agencyMedical Devices - Piezoelectric transducers used for low-frequency calibration of hydrophonesMedical Equipment - U.S. FDA 510(k) clears new dose calculator for radiotherapy treatment plansNeuroscience - Transgenic mice show Notch signaling is important for synaptic plasticityNon-Small Cell Lung Cancer - Genentech and partner announce NDA completion for TarcevaNutrition - Panel advises more vegetable consumptionObesity Prevention - National report card shows states "failing" to check obesityObesity and Diabetes - Metabolic syndrome treatment strategies outlinedOphthalmology - Latinos have high levels of visual impairment and eye diseaseOphthalmology - Squalamine stems the growth of new blood vessels in mice with retinopathyOral Cancer - Oral cancer epidemic expected due to use of betel quid substitutesOvarian Cancer - Sensitivity, specificity of MS-obtained proteomic diagnostic patterns comparedPain Medicine - NSAIDs increase expression of cyclooxygenase in inflamed spinal cordsPain Treatment - New guidelines set for better pain treatmentParasitic Disease - Rapid response should bring parasitic epidemic in Afghanistan under controlPeptic Ulcers - FDA clears POCone Infrared SpectrophotometerPolicy - Government decides not to intervene and force down AIDS drug pricePrescription Drugs - U.S. customs seizes prescription drug shipment in MiamiPrion Disease - Bovine normal prion protein PrP(104-242) purified by HPHICProduct Licensing - Specialty drug company receives U.S. FDA approval for mint flavor nicotine gumProstate Cancer - Biopharmaceutical company provides update on DN-101 Plus Taxotere trialPsoriasis - Phase I trial results reported for PsoraxinePsoriatic Arthritis - E.U. CHMP recommends approval of REMICADE for PsAPublic Health - Method to measure radiation levels of building materials developedPulmonary Hypertension - HIV-related pulmonary hypertension reviewedRabies Vaccine - The use of rabies immune globulin by emergency physiciansRegulatory Issues - Cancer specialists propose new approval track for targeted drugsRenal Cancer - Drugs that manage angiogenesis slow renal cell carcinoma progressionRenal Cell Carcinoma - EMEA grants orphan drug designation to BAY 43-9006Restless Legs Syndrome - Study: Requip reduces periodic leg movements in patients with RLSSalmonella Vaccine - Immune responses to killed Salmonella vaccine investigatedSalmonella Vaccine - Oral immunization with RfaH mutant protects mice against salmonellosisSexual and Reproductive Health - Survey reveals surprising insights into parental attitudes toward teen sexShigellosis Epidemiology - Shigellosis incidence high in Peruvian soldiers in Amazon River basinSkin Infection - sNDA submitted for Merrem I.V. for complicated skin infectionsSmallpox - FDA accepts BLA filing for Vaccinia Immune GlobulinStreptococcus Vaccine - Streptococcus pneumoniae epidemiology from Portugal aids vaccine choiceStress Response - Chronic stress regulates neuroendocrine responses in laying hensSurvival & Mortality - Health care program lowers child and maternal mortality in BangladeshTapeworm - Two antigens for Taenia solium tapeworm infection characterizedTobacco Use - Exposure to cigarette smoke affects antibody responses to oxidized LDLTuberculosis - New blood test to detect TB infection not affected by BCG vaccinationTuberculosis - TB infection interferon-gamma-based assay using new antigens developedTuberculosis Vaccine - Macrophage apoptosis in host immunity to mycobacterial infections reviewedTuberculosis Vaccine - T-cell epitopes on novel protective antigen of M. tuberculosis identifiedVirology - A sequence essential for virus replication has been identifiedWeight Loss - Organochlorine pollution affects weight loss in obese individualsWest Nile Virus - West Nile Virus introduced into Harris County, Texas, in 2002
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