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Alzheimer Disease
Transgenic animal models of Alzheimer disease reviewed
September 5th, 2004
Researchers review transgenic animal models of Alzheimer disease and related disorders in a recent issue of Molecular Psychiatry. "Alzheimer disease (AD) is a devastating neurodegenerative disease that affects more than 15 million people worldwide. Within the next generation, these numbers will more than double. To assist in the elucidation of pathogenic mechanisms of AD and related disorders, such as frontotemporal dementia (FTDP-17), genetically modified mice, flies, fish, and worms were developed, which reproduce aspects of the human histopathology, such as beta-amyloid-containing plaques and tau-containing neurofibrillary tangles (NFT)," investigators in...
Source: Medical Letter on the CDC & FDA (2004-09-05)
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