Addiction Medicine
Buprenorphine for treatment of opiate dependence reviewed
Published in Medical Letter on the CDC and FDA, September 5th, 2004
According to a study from the United States, "Buprenorphine's physiological effects are produced when it attaches to specific opiate receptors that are designated mu, kappa, or delta. Buprenorphine, a partial agonist at the mu receptor and an antagonist at the kappa receptor, produces typical morphine-like effects at low doses. At higher doses, it produces opiate effects that are less than those of full opiate agonists."
"Knowledge of the physiological effects of opiate receptors and the way they interact with...
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