Susan Hasty, Publisher
Table of Contents . . . September 19th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications
Antimicrobial Resistance - Mutation spectra provide insights into quinolone resistance in Salmonella
Diabetes - Tools available to promote diabetes prevention
Environmental Health - Perfluorinated organic acids and amides in human serum and milk measured
Food-Borne Illness - Modifications of Charm II assay for chloramphenicol in honey described
Lymphoma Therapy - Rac1 inhibits apoptosis in human lymphoma cells
Accreditation - Overhaul urged for accreditation of medical labs
Addiction Medicine - Chronic alcohol consumption accelerates T cell-mediated liver injury
Allergy Medicine - Preparation of benzylpenicilloyl-polylysine described
Allergy Medicine - Rules on asthma inhalers in schools outlined
Allergy Medicine - Variation of analytical results for peanuts in chocolate determined
Alzheimer Disease - Red blood cells may help spread vascular amyloidosis
Anthrax - Government collecting blood from vaccinated soldiers to create treatment
Anthrax - IND accepted by FDA for anthrax immunity-stimulating molecule
Artificial Heart - CardioWest artificial heart could get federal approval this year
Avian Influenza - World Health Organization says more funding needed to investigate bird flu
Bioterrorism - Contract awarded for joint biological point detection systems
Bioterrorism - Ebola and Marburg hemorrhagic fever potential agents for biologic warfare
Bioterrorism - Novel method estimates time and size of bioterror attack for real-time use
Bovine Spongiform Encephalopathy - French BSE epidemic in the late 1980s was completely undetected
Breast Cancer - FDA approves Taxotere for the treatment of women with early-stage breast cancer
Breast Implants - Supplemental data for silicone gel-filled breast implant PMA submitted to FDA
Cancer Detection - Molecular markers available for detection and progression of prostate cancer
Cancer Therapy - FDA approves Alimta for second-line treatment of advanced lung cancer
Cancer Therapy - Pharma company reports 2004 financial results, remains optimistic
Cardiac Arrest - Cardiology products provider and Quinton Cardiology will manufacture AED
Childhood Immunization - New vaccine is an important step forward
Collaborations - CRO joins Spacelabs Medical Data in strategic partnership
Coronary Artery Bypass - Vascular medical device developer and Boston Scientific collaborate
Coronary Stent - FDA approves extension of expiration date for TAXUS Express2 stent system
Dental Devices - FDA gives clearance for new dental copings, bridges, and veneers material
Depression - FDA updates its review of antidepressant drugs in children
Diabetes Genomics and Genetics - Targeted disruption of IA-2beta gene does not prevent diabetes
Drug Abuse - Data show increased abuse of methamphetamine in midwest, east, south
Drug Addiction - THC elevates beta-endorphin levels in ventral tegmental area
Drug Resistance - Screening system designed for novel HIV protease inhibitors in E. coli
Environmental Health - Dioxin alters human low-density lipoprotein structure
Fibromyalgia - Corgenix & partner complete development of fibromyalgia test kit
Finance - CRO reports revenues of $3.8 million, lower than the same quarter of last year
Finance - Drug-development company discusses second-quarter losses
Finance - GLIADEL maker reports 2004 second-quarter results
Finance - Glucose-monitoring company reports quarterly revenues of $47,000
Finance - RBX maker sees strong earnings growth for 2004 and 2005
Finance - Ultrasound-imaging company raises $27.1 million in equity financing
Finance - Vaccine maker reports increased revenues, provides quarter and 6-month update
Food-Borne Illness - Sensitivity analysis methods based on food safety risk applications compared
Genomics - Yale University, collaborator receive phase I NIH grant for MC2R discovery
HIV/AIDS Epidemiology - HIV cases increasing in Japan among gay men and young adults
HIV/AIDS Epidemiology - HIV estimate/projection for areas of low level/concentrated epidemics determined
HIV/AIDS Epidemiology - HIV prevalence is high in drug users and commercial sex workers in Myanmar
HIV/AIDS Epidemiology - HIV/AIDS epidemic in China in the rapid expansion phase
HIV/AIDS Exposure - New guidelines maximize effects of occupational HIV post-exposure prophylaxis
HIV/AIDS Research - Cell fusion does not correlate with syncytium formation
HIV/AIDS Screening - Rapid HIV test decreases post-exposure prophylaxis after occupational exposure
HIV/AIDS Therapy - Company to provide access to new HIV therapy Truvada
HIV/AIDS Vaccine - Generex expands HIV vaccine efforts with MGH investigator
Hantavirus - CDC looking for cause of hantavirus as victim recovers
Heart Attack - FDA grants clearance to market Powerheart AED G3 PRO defibrillator
Hemorrhagic Colitis - Probiotic treatment prevents/treats enterohemorrhagic E. coli O157:H7 infection
Immunology - Virus-specific T cell response doesn't endure after hepatitis C therapy
Infectious Disease - World facing "silent emergency" as billions struggle without basic sanitation
Influenza - Company produces further pandemic-like influenza vaccines for NIH studies
Influenza - U.S. prepares for possible flu outbreak
Influenza Vaccine - CDC says tainted flu vaccine may cause slight delay, but no shortage
Liquid Stable Reagents - FDA issues 510(k) clearance for liquid stable reagents
MRI Safety - HiResolution bionic ear system proven safe for MRI
Macular Degeneration - Clinical results for SnET2 presented at ASRS meeting
Macular Degeneration - FDA accepts NDA for Macugen (pegaptanib sodium injection)
Malaria - Simple weekly percentile alert threshold algorithm detects malaria epidemics
Malaria Vaccine - Plasmodium growth factor-like motifs needed for erythrocyte invasion
Medical Devices - Company signs technology license agreement to embed EKGs in cellular phones
Medical Technology - U.S. Patent Office issues two patents to pharmaceutical and diagnostics company
Mergers & Acquisitions - FTC clears acquisition of Cima Labs
Natural Products - Natural products and related compounds from marine sources are in trials
Nicotine - Role of nicotinic acetylcholine receptors in adipocytes investigated
Nutrition - Study: Americans don't eat enough produce
Obesity Genomics & Genetics - Missense substitution in fatty acid synthase gene linked to body fat
Occupational Safety - Lab's experience managing potential threats offers guidelines for others
Pancreatic Islets - Muscarinic stimulation of insulin abolished in M3 -deficient mice
Parapertussis - Bordetella parapertussis strains in Poland characterized
Pharmacokinetics - Bioavailability of two cefadroxil products found comparable
Poison Control - Acetaminophen overdose is major cause of hepatic failure in U.S.
Polio - New polio cases confirmed in Guinea, Mali and the Sudan
Poliomyelitis - India's antipolio campaign meets resistance among poor in eastern Bihar state
Primary Care Practice - New study shows critical role for primary care specialists
Prion Disease - Immunoprecipitation of prion protein mediated by antibodies
Product Licensing - Ultrasound skin permeation device is FDA cleared for use with topical lidocaine
Public Health - Direct-to-consumer prescription drug advertising has educational potential
Public Health - Local variation in public health preparedness outlined
Public Health - Monte Carlo analysis estimates polyacrylamide dose from skin-care products
Q Fever - Abandoned sheep slaughterhouse and wind causes Q fever outbreak
Q Fever - Aerosolization from renovation work possible cause of Q fever outbreak
Q Fever - Wind plays a role in Coxiella burnetii transmission
Regulatory Issues - FDA's regulatory role in the ICCVAM process outlined
Renal Cell Carcinoma - FDA grants fast-track status to temsirolimus
Rotavirus Vaccine - VP7 gene phylogenetic sequence lineage 1 rotavirus better for vaccines
SARS Outbreak - Multiple model parameters needed simultaneously to control SARS outbreaks
SARS Risk Factor - Human leukocyte antigens linked to SARS susceptibility and resistance
Schistosomiasis - Schistosome proteins play roles in host-parasite interactions
Smallpox Therapy - Antiviral prophylaxis of smallpox reviewed
Stroke - FDA clears device for removing blood clots in stroke patients
Systemic Lupus Erythematosus - Prestara clinical trial GL02-01 for women with lupus is complete
Tuberculosis - Simpler treatment schedules and newer drugs needed to combat TB in Africa
Tuberculosis - Universal measures to control TB in resource-poor countries inappropriate
Tuberculosis Vaccine - M. tuberculosis and M. bovis BCG induce equal protection
Tularemia - Tularemia signs/symptoms awareness can decrease morbidity during terror attack
Typhoid Fever Vaccine - Profile of travelers needing typhoid fever vaccination reported
Vectors and Zoonoses - Prevalence of E. coli O157:H7 in white-tailed deer from Louisiana determined
Viral Genotyping - A web-based resource identifies genotypes of HIV/HCV/HBV sequences
Waterborne Pathogens - Genomic research is necessary to identify emerging waterborne pathogens
Weight Loss - Saving room for dessert may help dieters
Women's & Children's Health - WHO: Pakistan's maternal and child health policy needs work
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.