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Nicotine

Role of nicotinic acetylcholine receptors in adipocytes investigated

Published in Medical Letter on the CDC and FDA, September 19th, 2004

Scientists report the results of a study on the expression and functional role of nicotinic acetylcholine receptors in rat adipocytes in a recent issue of the Journal of Pharmacology and Experimental Therapeutics.

According to a study from Japan, "To clarify whether nicotine has a direct effect on the function of adipocytes, we evaluated nicotinic acetylcholine receptor (nAChR) expression in adipocytes by reverse transcriptase-polymerase chain reaction (RT-PCR) and immunocytochemistry and the direct effects of nicotine on the production of adipocytokines by enzyme-linked immunosorbent assay and Western blot analysis. Receptor binding assays were performed using...

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