Animal Models
Animal models are guiding development of new immunotherapies for cancer
Published in Medical Letter on the CDC and FDA, October 10th, 2004
According to recent research published in the Journal of Leukocyte Biology, "Immunotherapy using adoptive cell transfer is a promising approach that can result in the regression of bulky, invasive cancer in some patients. However, currently available therapies remain less successful than desired. To study the mechanisms of action and possible improvements in cell-transfer therapies, we use a murine model system with analogous components to the treatment of patients."
"T cell receptor transgenic CD8+ T cells (pmel-1) specifically recognizing the melanocyte...
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