Environmental Health

Extraction method to measure halogenated compounds in breast milk developed

Published in Medical Letter on the CDC and FDA, October 10th, 2004

Scientists have developed a semiautomated high-throughput extraction and cleanup method for the measurement of polybrominated diphenyl ethers and polybrominated and polychlorinated biphenyls in breast milk.

"A semiautomated extraction and cleanup method has been developed to measure eight polybrominated diphenyl ethers (PBDEs), 2,2',4,4',5,5'-hexabromobiphenyl (BB-153), and 2,2',4,4',5,5'-hexachlorobiphenyl (CB-153). The method employs solid-phase dispersion on diatomaceous earth in a solid-phase extraction cartridge followed by automated addition of internal standards (¹³C-labeled). Extraction is then performed using an automated modular solid-phase...

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Source: Medical Letter on the CDC and FDA (2004-10-10)

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